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Arizona Diamondbacks vs. Philadelphia Phillies prediction, pick for MLB on Friday 4/10/26

Arizona Diamondbacks vs. Philadelphia Phillies prediction, pick for MLB on Friday 4/10/26

Published:

By: Brendan O'Sullivan

The Diamondbacks and Phillies begin a three-game series on Friday, April 10.

Philadelphia is a -194 moneyline favorite, while Arizona is +159 on DraftKings Sportsbook. The game total is set at over/under 8.5 runs.

Let’s get into a pick and prediction for this Diamondbacks vs. Phillies game.

Diamondbacks vs. Phillies prediction, preview

The weekend brings a new series for these two National League squads. The Phillies wrapped up their series vs. the Giants on Wednesday, while the Diamondbacks finished their series vs. the Mets on Thursday. Rest will be on the side of Philadelphia.

The Diamondbacks remain on the road, but they’re traveling from New York to Philadelphia—not a long trip. Arizona played a competitive series against New York, and now get another challenge on the road.

The Phillies are expected to compete for the NL East again, but they haven’t gotten off to a hot start. They’re 6-6 and got shut out in back-to-back games against the Giants. Those losses were shocking since Cristopher Sanchez and Aaron Nola started. Jesus Luzardo will start the first game against Arizona after an 11-strikeout performance in his last outing.

Michael Soroka is on the mound for the Diamondbacks as he continues his strong start to the season. He’s allowed one earned run across 10 innings, while striking out 13 batters. His two other starts were against the Tigers and Braves, two quality lineups. The Phillies may be the biggest challenge yet, but it’s something Soroka has built himself up to thus far.

Diamondbacks vs. Phillies Pick, Best Bet

The Phillies needed an off day after scoring zero runs in the past two games against the Giants. Perhaps a reset and a return home will do the team wonders moving forward. A 6-6 record at this point of the season is not suitable for a potential division winner.

While Philadelphia will bounce back this season, I’m a believer in Soroka’s hot start. I think the Phillies struggle in this one.

Best Bet: Arizona Diamondbacks ML (+159)

I am a promoter at DraftKings and am also an avid fan and user (my username is osullivanb255) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.