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Wondering what bets are popular among the public today? With DraftKings Network’s Player Props Page, all of this information is at your disposal. The Player Props tool provides all of the most bet player props by handle + odds on the DraftKings Sportsbook, updated as regularly as every five minutes!

I’ve taken today’s most popular MLB player props on DraftKings Sportsbook and broken down exactly why the public is so fond of these, helping you make informed picks ahead of Friday’s MLB slate.


TODAY’S MOST BET MLB PLAYER PROPS

Event Event Date Market Betslip Line Odds
ATL Braves @ MIA Marlins 9/26, 04:10PM Matt Olson Home Runs 1+ +400
PIT Pirates @ DET Tigers 9/26, 01:10PM Oneil Cruz Home Runs 1+ +336
NY Mets @ WAS Nationals 9/26, 12:35PM Juan Soto Home Runs 1+ +464
NY Mets @ WAS Nationals 9/26, 12:35PM James Wood Home Runs 1+ +450
CIN Reds @ TOR Blue Jays 9/26, 03:07PM Elly De La Cruz Home Runs 1+ +517
LA Dodgers @ SF Giants 9/26, 04:05PM Teoscar Hernandez Home Runs 1+ +402
CIN Reds @ TOR Blue Jays 9/26, 03:07PM Sal Stewart Home Runs 1+ +680
STL Cardinals @ MIL Brewers 9/26, 07:10PM Jackson Chourio Home Runs 1+ +424
ATL Braves @ MIA Marlins 9/26, 04:10PM Griffin Conine Home Runs 1+ +498
COL Rockies @ CHI White Sox 9/26, 07:10PM Davis Martin Strikeouts Thrown 5+ +124
LA Dodgers @ SF Giants 9/26, 04:05PM Shohei Ohtani Home Runs 1+ +282
PIT Pirates @ DET Tigers 9/26, 01:10PM Brandon Lowe Home Runs 1+ +436

Note: The table above is updated as regularly as every five minutes, so odds are likely to change.


BREAK IT DOWN:

(stats taken from DraftKings Sportsbook’s Stats Hub)

Shohei Ohtani 1+ Home Run (+161): Look, I think Ohtani could be going up against prime Roger Clemens and he’d still be among the most popular home run bets on the slate. That’s just how this works. He’s Shohei Ohtani. He’s won three straight MVP Awards and no one’s hit more long balls since the beginning of 2023 (153). All that said, Ryne Nelson’s a decent major league pitcher that absolutely shut down opposing LHBs last year. To wit, lefties slashed just .191/.256/.309 off Nelson with a .251 wOBA — the third-lowest mark of any qualified pitcher. These trends have played out across the pair’s past meetings, as well, with Ohtani just 2-for-13 with a .406 OPS.

Vladimir Guerrero Jr. 1+ Home Run (+321): Guerrero as a pure power bat is always an interesting scenario. Does Vladdy possess elite pop? Of course. Yet the former top prospect has always seemed to prefer to hit for average rather than hunting home runs. In fact, despite over 680 plate appearances in each of the past three seasons, Guerrero’s only hit 30-plus long balls once. Still, 97th percentile bat speed (76.7) and a 96th percentile expected wOBA (.384) are pretty alluring. I can understand why the public is backing him in his first contest in Toronto since Game 7 of the World Series. Luis Severino only surrendered 0.67 opponent home runs per nine away from Sacramento in 2025, yet Vladdy should also get a couple cracks at an underwhelming A’s bullpen.

Sandy Alcantara 6+ Strikeouts Thrown (-110): Despite being a former Cy Young Award winner with great stuff, Alcantara’s never really been a strikeout artist. That was made painfully clear in 2025, as the right-hander posted just a 9.3% swinging strike — easily a career-low. The popularity of this prop isn’t about Alcantara, though. It’s almost certainly about the Rockies. Colorado was the worst lineup in baseball when playing at normal altitude in 2025, struggling to a .203 average with a 63 wRC+. The Rockies also had the highest strikeout rate within the split at 28.6%, because of course they did. Look for Sandy to take advantage.


3-Pick Same Game Parlay

Taking three of the most-bet player props individually is always an option, but why not roll them into a same game parlay (SGP) and get in on all the action at once? It’s a fun way to tie everything together — feel free to tag along.

Shohei Ohtani 1+ Home Run (+161)

Vladimir Guerrero Jr. 1+ Home Run (+321)

Sandy Alcantara 6+ Strikeouts Thrown (-110)

Parlay Odds: +1997

Head straight to the DraftKings Sportsbook to place these bets, OR check out the Player Props Page tool on DKN.com for more options before you fill out your slips!


Garion is a Toronto-based writer who has been playing fantasy sports since elementary school. With a particular affinity for advanced statistics and sabermetrics, he’s been covering DFS Baseball, Football and Basketball for DraftKings dating back to 2018. Prior to that, Garion’s work could be found at FNTSY, SportsGrid, HoopsHype, The New York Daily News and Sportsnet.ca. Still, he is a Dolphins fan, so his decision-making can be questioned from time-to-time.
Disclaimer

All views expressed are my own. I am an employee of DraftKings and am ineligible to play in public DFS or DKSB contests.