Looking for today’s MLB probable pitchers? Below is the full list of starting pitcher matchups for today’s slate, including game times and embedded widgets with odds, strikeout props, and team trends. You can also find the latest odds and player props on DraftKings Sportsbook.
Top Pitching Matchups Today
- Tarik Skubal opens his Cy Young defense against the Padres
- Zac Gallen vs. Yoshinobu Yamamoto headlines the late slate
- Logan Gilbert brings elite strikeout upside vs. Cleveland
- Paul Skenes debuts against a revamped Mets lineup
Pittsburgh Pirates vs. New York Mets Probable Pitchers
- Pittsburgh Pirates: Paul Skenes
- New York Mets: Freddy Peralta
- Time: 1:15 PM ET
Paul Skenes takes the ball for the Pirates against newly acquired Mets pitcher Freddy Peralta.
Chicago White Sox vs. Milwaukee Brewers Probable Pitchers
- Chicago White Sox: Shane Smith
- Milwaukee Brewers: Jacob Misiorowski
- Time: 2:10 PM ET
Shane Smith looks to build off a solid 2025 rookie campaign and takes on the team that signed him as an undrafted free agent. The Brewers will start a star of their own, Jacob Misiorowski, who had an 11.8 K/9 66 IP in 2025.
Washington Nationals vs. Chicago Cubs Probable Pitchers
- Washington Nationals: Cade Cavalli
- Chicago Cubs: Matthew Boyd
- Time: 2:20 PM ET
Cavalli, a former first round pick for the Nationals, is coming off a strong Spring Training. He’ll look to build upon his 14 shutout Spring Training innings in his first start of 2026. The Cubs will oppose with Matthew Boyd, who had a career resurgence last season with a 3.21 ERA and a 3.75 xERA.
Minnesota Twins vs. Baltimore Orioles Probable Pitchers
- Minnesota Twins: Joe Ryan
- Baltimore Orioles: Trevor Rogers
- Time: 3:05 PM ET
Joe Ryan will start for the Twins after it was widely speculated he would be traded during the offseason. He’ll oppose Trevor Rogers, who could see some regression in 2026 after his 1.80 ERA was accompanied by a 3.40 xERA.
Boston Red Sox vs. Cincinnati Reds Probable Pitchers
- Boston Red Sox: Garrett Crochet
- Cincinnati Reds: Andrew Abbott
- Time: 4:10 PM ET
Plenty of noise has been made about the poor Spring Training from Garrett Crochet, who ended with a 7.36 ERA and just a 4.8 K/9 through 14.2 innings. Will that carry over into the regular season? He’ll be opposed by Andrew Abbott who flourished at home last season with a 2.39 ERA and a 3.82 FIP.
Detroit Tigers vs. San Diego Padres Probable Pitchers
- Detroit Tigers: Tarik Skubal
- San Diego Padres: Nick Pivetta
- Time: 4:10 PM ET
The reigning American League Cy Young winner Tarik Skubal will take the hill for the Tigers once again on Opening Day. Nick Pivetta gets the nod for the Padres after producing a career-low 2.87 ERA in 2025.
Los Angeles Angels vs. Houston Astros Probable Pitchers
- Los Angeles Angels: Jose Soriano
- Houston Astros: Hunter Brown
- Time: 4:10 PM ET
Jose Soriano will look to keep his infield busy after posting a career-high 65% ground ball rate in 2025. He’ll be opposed by Hunter Brown, who draws a free swinging Angels lineup to start his 2026 campaign.
Texas Rangers vs. Philadelphia Phillies Probable Pitchers
- Texas Rangers: Nathan Eovaldi
- Philadelphia Phillies: Cristopher Sanchez
- Time: 4:15 PM ET
Nathan Eovaldi is coming off one of his best individual seasons and headlines the Rangers rotation in 2026. Sanchez is also doing the same and will make his first start after signing a six-year, $107 million extension with the Phillies.
Tampa Bay Rays vs. St. Louis Cardinals Probable Pitchers
- Tampa Bay Rays: Drew Rasmussen
- St. Louis Cardinals: Matthew Liberatore
- Time: 4:15 PM ET
Despite a 2.76 ERA and a 3.48 xERA, Rasmussen doesn’t get talked about enough for being a solid starter in the American League. He’ll face a former top prospect in Matthew Liberatore, who hasn’t exactly lived up to the hype he once had.
Arizona Diamondbacks vs. Los Angeles Dodgers Probable Pitchers
- Arizona Diamondbacks: Zac Gallen
- Los Angeles Dodgers: Yoshinobu Yamamoto
- Time: 8:30 PM ET
Gallen looks to bounce-back from an unusually tough year after posting a 4.83 ERA with a 4.28 xERA, both career-highs. He’ll oppose Yoshinobu Yamamoto, who had a 10.8 K/9 through 30 innings against the Diamondbacks in 2025.
Cleveland Guardians vs. Seattle Mariners Probable Pitchers
- Cleveland Guardians: Tanner Bibee
- Seattle Mariners: Logan Gilbert
- Time: 10:10 PM ET
Bibee hopes that his Spring Training doesn’t carry over to Opening Day, after posting a 6.65 ERA and a 5.52 FIP through 23 innings. He’ll be opposed by Logan Gilbert who posted an 11.8 K/9 across 66 innings in 2025.
