Searching for the best March Madness parlays today? Thursday’s Sweet 16 slate tips off at 7:10 p.m. ET with four games on the schedule. That creates plenty of opportunities for spreads, game totals, and longshot bets on DraftKings Sportsbook. Browse today’s featured picks below and add your selections directly to your bet slip.
These March Madness parlays focus on spreads, totals, and game scripts across Thursday’s Sweet 16 matchups, highlighting a mix of top seeds, underdogs, and high-upside betting angles.
Best NCAA Tournament Parlays for March 26, 2026
Below are today’s featured March Madness parlays available on DraftKings Sportsbook. Click “Add to Bet Slip” to place your wager instantly in the DraftKings app. These March Madness parlays focus on spreads, totals, and game scripts across Thursday’s Sweet 16 matchups.
Barstool Sports Sweet 16 Spread Picks
Ride with the PMT crew as they pick their favorite Thursday CBB lines!
- #4 Nebraska -1.5 (vs Iowa)
- #4 Arkansas +8.5 (vs Arizona)
- #11 Texas +7.5 (vs Purdue)
Stephen A. Smith Sweet 16 Spread Picks
The ESPN host & analyst is backing these three College Basketball lines!
- #1 Arizona -8.5 (vs Arkansas)
- #2 Purdue -7.5 (vs Texas)
- #2 Houston -2.5 (vs Illinois)
NCAA Tournament Top Seed Spread Parlay
#1 Seeds for a reason! Bet on the remaining top seeds to cover & advance to Elite 8
- #1 Arizona -8.5 (vs Arkansas)
- #1 Duke -6.5 (vs St. Johns)
- #1 Michigan -9.5 (vs Alabama)
Rico Bosco’s Sweet 16 Parlay Picks
Barstool Sports personality Rico Bosco crafts a CBB parlay for the Sweet 16!
- #2 Houston to Win (vs Illinois)
- #4 Alabama to Win (vs Michigan)
- #4 Arkansas +8.5 (vs Arizona)
- IOWA vs NEB: Over 131.5 Points
March Madness Sweet 16 Race to 10 Points Parlay
Ride the higher ranked seeds to win the Race to 10 in their respective matchups
- #1 Arizona to Win Race to 10 Points
- #2 Purdue to Win Race to 10 Points
- #2 Houston to Win Race to 10 Points
- #4 Nebraska to Win Race to 10 Points
Check out our NCAA Tournament coverage with picks, predictions for every game on DraftKings Network!
Sweet 16 Game Total Over Parlay
- ILL vs HOU: Over 140.5 Points
- TEX vs PUR: Over 147.5 Points
- SJU vs DUKE: Over 141.5 Points
- TENN vs ISU: Over 140.5 Points
Check out all our parlays for every sport on the DraftKings Network Parlay Page!
