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Opening Odds for Duke Blue Devils vs. St. John’s Red Storm in March Madness 2026 Sweet 16

Opening Odds for Duke Blue Devils vs. St. John’s Red Storm in March Madness 2026 Sweet 16

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By: Ciaran Doyle

Duke was dominant in the second half against TCU to book themselves a spot in the Sweet 16. The game was close throughout, until the Blue Devils pulled away down the stretch to ultimately win 81-58. Cameron Boozer led the team with 19 points in the win.

The Johnnies looked to have the win secured early against Kansas, but the Jayhawks stormed back and tied the game with 13 seconds remaining. Fortunately for the Johnnies, Dylan Darling made a clutch game-winning layup as time expired to give St. John’s the win.

The Blue Devils open as a 6.5-point favorite on DraftKings Sportsbook, with St. John’s listed at +210 on the moneyline. The points total is set at O/U 141.5.

This game will take place on Friday, March 27th at the Capital One Arena in Washington, DC.

I am a promoter at DraftKings and am also an avid fan and user (my username is ciarandoyle77) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.