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Best March Madness Parlays Today for Sunday, March 22 (Round of 32 Picks)

Best March Madness Parlays Today for Sunday, March 22 (Round of 32 Picks)

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By: Steve Buchanan

Searching for the best March Madness parlays today? Sunday’s NCAA Tournament slate tips off at 12:10 p.m. ET with 8 games on the schedule. That creates plenty of opportunities for player props, spreads, and longshot bets on DraftKings Sportsbook. Browse today’s featured picks below and add your selections directly to your bet slip.

These March Madness parlays target a mix of favorites, underdogs, and game totals across Sunday’s Round of 32 matchups to balance safer plays with higher-upside returns.

Best NCAA Tournament Parlays for March 22, 2026

Below are today’s featured March Madness parlays available on DraftKings Sportsbook. Click “Add to Bet Slip” to place your wager instantly in the DraftKings app. These March Madness parlays focus on spreads, totals, and game scripts across Sunday’s Round of 32 matchups.

NCAA Tournament Top Seeds Spread Parlay

  • #1 Florida -10.5 (vs Iowa)
  • #1 Arizona -11.5 (vs Utah State)
  • #2 Purdue -7.5 (vs Miami FL)
  • #2 Iowa State -4.5 (vs Kentucky)

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March Madness Underdog Moneyline Parlay

  • #4 Kansas to Win (vs St. Johns)
  • #9 Iowa to Win (vs Florida)

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NCAA Tournament Game Total Parlay

  • UK vs ISU: Over 145.5 Points
  • SJU vs KU: Over 144.5 Points
  • TENN vs UVA: Over 137.5 Points
  • IOWA vs FLA: Over 145.5 Points

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March Madness Race to 10 Points Parlay

  • #2 Purdue to Win Race to 10 Points
  • #2 Iowa State to Win Race to 10 Points
  • #3 Virginia to Win Race to 10 Points
  • #5 St. Johns to Win Race to 10 Points

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March Madness Blowout Win Parlay (21+ Points)

  • #1 Florida to Win by 21+ (vs Iowa)
  • #1 Arizona to Win by 21+ (vs Utah State)

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Check out our NCAA Tournament coverage with picks, predictions for every game on DraftKings Network!


March Madness Top Seed Moneyline Parlay Picks

  • #1 Florida to Win (vs Iowa)
  • #1 Arizona to Win (vs Utah State)
  • #2 UConn to Win (vs UCLA)
  • #3 Virginia to Win (vs Tennessee)
  • #4 Alabama to Win (vs Texas Tech)

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NCAA Tournament Game Total Under Parlay

  • IOWA vs FLA: Under 145.5 Points
  • USU vs ARIZ: Under 154.5 Points
  • UCLA vs UCONN: Under 136.5 Points
  • TTU vs ALA: Under 165.5 Points

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March Madness Underdog Upset Parlay Picks

  • #4 Alabama to Win (vs Texas Tech)
  • #7 UCLA to Win (vs UConn)
  • #9 Utah State to Win (vs Arizona)

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NCAA Tournament To Win Both Halves Parlay

  • #2 UConn to Win Both Halves (vs UCLA)
  • #5 Texas Tech to Win Both Halves (vs Alabama)

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Texas Tech vs. Alabama Same Game Parlay

  • TTU vs ALA: Both to Score 87+ Points
  • Yes – Game to Have Overtime

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#1 Arizona Same Game Parlay Picks

  • #1 Arizona to Win by 21+ (vs Utah State)
  • Arizona to Win First 4 Minutes
  • ARIZ vs USU: Over 154.5 Points

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Check out all our parlays for every sport on the DraftKings Network Parlay Page!

All views expressed are my own. I am an employee of DraftKings and am ineligible to play in public DFS or DKSB contests.