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Opening Odds for Duke Blue Devils vs. TCU Horned Frogs in March Madness 2026 Second Round

Opening Odds for Duke Blue Devils vs. TCU Horned Frogs in March Madness 2026 Second Round

Sports Betting Picks College Basketball 2026

Published:

By: Ciaran Doyle

Duke avoided a massive scare in the First Round of the tournament, coming from behind to beat #16 seed Siena 71-65. They trailed by 11 at the half, but rallied down the stretch. Regardless, they still managed to win the game and have now booked themselves a spot in the Second Round against TCU. Star forward Cameron Boozer led them with 22 points.

The Horned Frogs were in a tight game themselves on Thursday, but they outlasted #8 seed Ohio State 66-64. TCU was led by Xavier Edmonds, Micah Robinson and David Punch who all scored at least 16 points. The next highest scorer for the Horned Frogs was Brock Harding with only eight points.

The Blue Devils open as a 12.5-point favorite on DraftKings Sportsbook, with TCU listed at +575 on the moneyline. The points total is set at O/U 137.5.

This game will take place on Saturday, March 21st at the Bon Secours Wellness Arena in Greenville South Carolina.

Ciaran Doyle

I am a promoter at DraftKings and am also an avid fan and user (my username is ciarandoyle77) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.