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Real Madrid vs. Man City prediction, pick for Wednesday 3/11/26

Real Madrid vs. Man City prediction, pick for Wednesday 3/11/26

Published:

By: Ciaran Doyle

The UEFA Champions League Round of 16 has arrived as Man City will travel to Spain to take on Real Madrid on Wednesday.

Madrid disposed of Benfica in the playoff round to advance, while Man City automatically qualified for this stage of the tournament after finishing eighth in the League Phase.

Man City are +100 favorites on the moneyline, while a draw is available at +285. Fancy a Real Madrid upset? They are +240 on the moneyline on DraftKings Sportsbook.

Real Madrid vs. Man City Prediction, Pick

The standout matchup of the Round of 16 is undoubtedly Real Madrid facing off against Man City once again. These teams are more than familiar with one another, as they will face off in the knockout rounds of the Champions League for the fifth consecutive season. On top of that, they played each other in the League Phase of this year’s competition, with Man City coming out 2-1 victors.

Let’s go through some of the recent knockout results.

Last season, these teams faced off in the playoff round. Real Madrid won both legs, advancing 6-3 on aggregate. In the 2023/24 quarter-finals, it took a penalty shootout to separate the teams, with Real Madrid advancing. In 2022/23, it was Man City who advanced in the semi-finals with a 5-1 aggregate win. In 2021/22, Real Madrid narrowly advanced in the semi-finals.

In three of the last four knockout matchups Real Madrid have advanced, and they did not lose at the Bernabéu in all four of those knockout rounds.

While Man City might be the more in-form team, we all know that Real Madrid step up their game in the knockout stages of the Champions League. I am surprised they are this big of an underdog, and although they might not advance, I think they are more than capable of winning the first leg.

In five home Champions League games this season, Real Madrid have won four times. In four away games for Man City, they won two, drew one and lost one. Only a single point separated these teams in the UCL League Phase table as City finished eighth while Madrid finished just outside automatic qualification in ninth.

This should be yet another closely contested, entertaining matchup between these teams. History says Real Madrid will likely win the first leg, and I agree.

Best Bet: Real Madrid Moneyline (+240)

Ciaran has been an editor for the DraftKings Network team since 2023. He graduated from the University of Arizona before attending Arizona State University for his master’s degree in sports journalism. Ciaran previously covered Phoenix Rising FC for Cronkite News before joining DraftKings. He is passionate about sports betting, and his biggest focus has always been on the NFL and soccer. You can find him on X at @Ciaran_Doyle7.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is ciarandoyle77) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.