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Seton Hall Pirates vs. DePaul Blue Demons prediction, pick for NCAAM on Wednesday 2/18/26

Seton Hall Pirates vs. DePaul Blue Demons prediction, pick for NCAAM on Wednesday 2/18/26

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By: Dan Johnson

Seton Hall’s season has a defined shape now, and the calendar is tightening around it. The Pirates are 18-8 overall and 8-7 in Big East play, sitting in the part of the table where every home game is résumé oxygen. DePaul arrive 13-12 and 5-9, still dangerous enough to make this feel personal because the Blue Demons already beat Seton Hall 67-60 in the first meeting. The number reflects that tension: the market is asking the Pirates to win this twice, once on the scoreboard and once on the margin. Below is my preview, prediction, and pick for tonight’s college basketball game between the Seton Hall Pirates and the DePaul Blue Demons.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Seton Hall vs. DePaul prediction, preview

Seton Hall rank 15th in defensive efficiency at 0.947 points allowed per possession, and they pair it with a 65.0 points per game scoring defense. DePaul are not a disaster defensively either, but they sit 65th in defensive efficiency at 1.007, which is a very different level of weekly resistance. The most glaring separator is shot quality suppression: the Pirates hold opponents to 40.2% shooting, a 48.5% opponent eFG, and a 45.0% opponent two-point clip. DePaul’s offense has a second gear at 1.101 points per possession, but the lane they want most is exactly the lane Seton Hall erase at the rim.

TSeton Hall’s best nights are built from one scorer catching fire while the defense keeps the game on rails. Adam Clark just dropped 31 in an 87-80 win over Providence, the kind of eruption that flips a low-total script into a comfortable cover. A few days later, Aj Staton-McCray hit 19 in a 63-56 win at Butler, and that’s the cleaner version of the Pirates’ identity: make it ugly, win the middle of the floor, then let one perimeter creator decide the separating stretch. DePaul’s counterpunch has names, too. NJ Benson is the interior hinge, coming off 23 points and 10 rebounds in a 72-71 win over Creighton, with Brandon Maclin adding 18, and CJ Gunn is the season-long lead voice at 13.8 points per game. If the Blue Demons threaten this number, it’s because that trio turn half-court possessions into efficient twos without coughing up live-ball runouts.

DePaul vs. Seton Hall pick, best bet

The argument against laying 8.5 is always the same in this scoring band: one cold pocket, and the spread turns into a hook problem. Seton Hall score only 68.4 points per game, they sit at 49.5% eFG, they take a microscopic 15.7 threes per game, and they shoot 70.5% at the line. That’s not a profile built for quick catch-up math if the wrong four-minute stretch hits. The rebuttal is that Seton Hall don’t need heat to create separation, because they manufacture extra possessions in ways that don’t require a jumper: they are No. 1 nationally in block rate at 10.8% and No. 2 in blocks per game at 6.2, and they rebound offensively at a 34.4% clip. DePaul have also been living small lately, averaging 63.8 points across their last four games while shooting 42.3%, and the road defensive floor has shown cracks in losses like 89-61 at St. John’s and 90-72 at Xavier. That’s exactly how a favorite gets to nine without playing pretty.

The context is simple and it matters, because it changes effort into measurable outcomes. The first meeting already put a bruise on Seton Hall’s pride, and this is the response spot at home, in the kind of building where physical defense usually gets rewarded early. That urgency tends to show up as harder closeouts and more bodies on the glass, which is exactly where Seton Hall already live with their offensive rebounding and rim protection. DePaul also arrive short-handed with Jalen Lorenz out and David Delalic out for the season, and a thinner rotation is not abstract here; it tends to become slower ball-handling late and softer box-outs when the game turns into a half-court wrestling match. DePaul do one thing that normally keeps underdogs alive, limiting opponents to 19.0 three-point attempts per game, but Seton Hall barely shoot threes anyway, so the Demons aren’t naturally taking away the Pirates’ favorite weapon.

So the bet is the one the number is begging for, as long as the handicap is built on repeatable defense and extra chances rather than a made-shot prayer. The board is sitting around Seton Hall -8.5 with a total near 130 and a moneyline around the -400 range, and other books have floated the spread in the -7.5 to -9 neighborhood. I’m laying it: Seton Hall -8.5, playable to -9.5.

Predicted score: Seton Hall 70, DePaul 60. If DePaul hit an above-band three-point night while staying tidy with the ball, the game can get trapped in the six-to-eight range late, but I expect Seton Hall’s rim deterrence and second-chance pressure to stretch it past the number.

Best bet: Seton Hall -8.5 (-110) vs. DePaul

Tail it with me in the DKN Betting Group here!

Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.