Every week, DraftKings Network analysts share their favorite NFL bets on DraftKings Sportsbook for each NFL game.
Below is a collection of the top NFL best bets for the NFL’s Week 18 betting card.
To see all DraftKings betting analysis, head over to the DraftKings Network sports betting picks page!
Check out the numerous NFL betting markets available on DraftKings Sportsbook!
Dan Johnson: Jacksonville Jaguars vs. Tennessee Titans prediction, pick
Picks below! Read Dan’s full betting analysis here: Jacksonville Jaguars vs. Tennessee Titans prediction, pick for NFL Week 18 on Sunday 1/04/26
Titans +13.5 (-115) at Jaguars
Parker Washington 60+ receiving yards (+160)
Keagan Smith: Indianapolis Colts vs. Houston Texans prediction, pick
Picks below! Read Keagan’s full betting analysis here: Indianapolis Colts vs. Houston Texans prediction, pick for NFL Week 18 on Sunday 1/4/26
IND Colts under 13.5 points (-110)
Brendan O’Sullivan: Bengals vs. Browns Best Prop Bets
Picks below! Read Brendan’s full betting analysis here: NFL Best Bets: Bengals vs. Browns Best Prop Bets for Week 18
Joe Burrow under 241.5 passing yards (-113)
Chase Brown anytime touchdown (-130)
Charlie Cummings: Packers vs. Vikings Best Prop Bets
Picks below! Read Charlie’s full betting analysis here: NFL Best Bets: Packers vs. Vikings Best Prop Bets for Week 18