The quarterfinals are complete, meaning there are just four teams left in the 2025 College Football Playoff. No. 1 Indiana, No. 5 Oregon, No. 6 Ole Miss and No. 10 Miami remain in the bracket.
The past round featured eventful games with Indiana blowing out No. 9 Alabama 38-3 and Oregon shutting out No. 4 Texas Tech 23-0. Miami kicked off the quarterfinals with a 24-14 upset over No. 2 Ohio State, ending the Buckeyes hopes for back-to-back titles. No. 6 Ole Miss defeated No. 3 Georgia 39-34 with a drama-filled ending to conclude the quarterfinals.
With the semifinals set, here’s a look at the updated College Football National Championship odds on DraftKings Sportsbook.

Indiana, the No. 1 team in the country, is still the favorite to win the national championship at +135 odds. The Hoosiers will play No. 5 Oregon on Friday, Jan. 9. These teams met on Oct. 11, when Indiana won 30-20, marking the Ducks’ only loss of the season.
Miami is tied with Oregon for the second best odds to win the championship at. +300. The Hurricanes will play No. 6 Ole Miss on Thursday, Jan. 8. The Rebels are +550 to win the title.