The Browns will host the Bills at Huntington Bank Field on Sunday afternoon. On DraftKings Sportsbook, Cleveland is a +490 underdog on the Moneyline, with the game’s total set at O/U 41.5 points.
Below, I’ll go over my favorite player prop bets on DraftKings Sportsbook for Sunday’s NFL Week 16 matchup between the Browns and Bills.
Browns vs. Bills Best Prop Bets
James Cook Longest Rush Over 15.5 Rushing Yards (-110)
The fourth-year back is having a career season and enters Week 16 ranked second in the NFL in rushing yards. While Cleveland’s run defense ranks second in rushing EPA and allows just 3.9 yards per carry, it has still been vulnerable to chunk plays, and Cook specializes in those. The Browns have given up 12 runs of 20+ rushing yards, while Cook ranks sixth in 20+ yard runs among running backs. The Bills have leaned on Cook heavily over the back half of the season, and he has logged 60% or more snaps in four of the past five games.
Quinshon Judkins 18+ Rushing Attempts (+105)
The rookie back has missed this mark in back-to-back games against the Titans and Bears; however, the Bills field one of the worst run defenses in the NFL. Buffalo allows 5.4 yards per carry and ranks 31st in rushing EPA, and Judkins is the exact type of back that presents issues for a Bills team that struggles with tackling. I’m expecting some struggle from the Bills, too, which should lead to a more balanced game script for the Browns offense, and that means plenty of run for Judkins. The 22-year-old has cleared this mark in 5-of-7 home games.