Week 13 of the 2025 NFL season continues with a great Monday Night Football game between the New York Giants and the New England Patriots. There are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this season is Pick6 Fantasy Football!
Here are my top Pick6 plays for Week 13 Monday Night Football.
TreVeyon Henderson More than 0.5 Rush + Receiving Touchdowns
It took some time to gain the coaching staff’s trust, but the Patriots’ second-round pick has become the featured back for the Patriots in recent weeks. Henderson proved himself during the stretch that Rhamondre Stevenson missed with injury, but even after Stevenson returned last week, Henderson controlled the backfield. Over the past five games, Henderson has averaged 96.2 scrimmage yards per game. He also has five touchdowns over that five-game stretch. He has been a weapon on the ground and in the receiving game for New England since taking over the backfield. Against the Giants, Henderson should dominate on the ground. The Giants rank dead last in the NFL in rushing yards per game allowed, defensive EPA/rush and defensive rushing success rate this season. New England should feed Henderson with regularity in this game, and he has a great chance to find the end zone at least once.

Jaxson Dart More Than 204.5 Passing Yards
Jaxson Dart is making his return for the Giants this week. After two starts for Jameis Winston while Dart was in concussion protocol, the rookie is ready to reclaim his offense. Dart was playing great football for the Giants before his injury and hopes to pick up where he left off. The Patriots have one of the best run defenses in the NFL, ranking second in rush yards per game allowed. The Giants will need to use the passing game to beat the Patriots, especially with Cam Skattebo out. New England ranks 17th in passing yards per game allowed and 20th in defensive dropback success rate. The Patriots have given up 45 passes of 20 yards or more this season, the second-most in the NFL. Dart should be able to hit a couple of deep balls against this shaky secondary. The Patriots are likely to put up points against the Giants’ defense, so Dart will need to throw to keep up with Drake Maye. That should lead to him throwing for at least 205 yards in this game.

Tyrone Tracy Jr. More Than 17.5 Receiving Yards
Tyrone Tracy Jr. has done a good job since Cam Skattebo went down with a season-ending injury. Tracy was a promising young talent in his rookie season, but Skattebo took over the backfield earlier this season after providing a major spark. Over the last three games, Tracy is averaging 113.3 scrimmage yards per game. Devin Singletary has been getting some work on the ground as well, but Tracy has been the primary back in passing downs. Over the last two games, Tracy has combined for 119 receiving yards. He has shown serious flashes of why he was such a well-regarded rookie last season. The Patriots have the second-best run defense in the NFL, so the Giants will likely try to get Tracy the ball in space in the passing game, rather than trying to run it between the tackles. Tracy has gone way over this receiving yards number in his past two games and he should clear it against New England as well.

What is DraftKings Pick6?
Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.
How to Play
Create a Pick Set
Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice, and you must pick players from at least two different teams.
Enter an Amount
Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.
Sweat Your Picks
When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.
Compete for Prizes
Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.
Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!