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Detroit Lions vs. Green Bay Packers prediction, pick for NFL Week 13 on Thanksgiving 11/27/25

Detroit Lions vs. Green Bay Packers prediction, pick for NFL Week 13 on Thanksgiving 11/27/25

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By: Dan Johnson

Thanksgiving in Detroit always feels like a family photo, and this one finally matters again. The Lions are chasing the Bears and Packers, trying to plant their flag on their own holiday. Green Bay walks in with Jordan Love playing like the division’s newest grown-up, even while the offense sputters lately. Detroit limps in without Sam LaPorta and Kerby Joseph, still carrying Dan Campbell’s bruising personality on defense. Short week, division tension, and a packed dome should make this feel closer to January than November. Below is my prediction for NFL Week 13’s Thanksgiving game between the Detroit Lions and the Green Bay Packers.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Lions vs. Packers prediction, preview

Detroit’s offense lives near the top of every basic column: 29.6 points and 378.5 yards per game. They rush for 139.8 a week at 5.1 a carry, then throw for 238.6 at 7.8 per attempt. Jared Goff sits around 69% completions with twenty-three touchdowns, five picks, and a steady 0.131 EPA per play. The engine is Jahmyr Gibbs and David Montgomery, combining for over 1,460 rushing yards and fifteen scores on the ground. Green Bay’s defense has quietly become the problem here, allowing 18.4 points and 278.7 yards, just 4.6 per snap. They live in zone on nearly eighty percent of dropbacks, blitzing only 18.2% but winning downs with discipline. Kelvin Sheppard’s group counters with 41.7% man coverage and a 27.4% blitz rate, chasing pressure rather than disguise. Detroit generates pressure on 49.8% of dropbacks; Green Bay’s line already allows heat on 47.4% of passes. That trench tension, not the shiny skill names, feels like the heartbeat of this game.

The easiest counter says Green Bay’s offense is simply better snap-to-snap and due for a bounce. Love owns the bigger total EPA number, 94.4 to Goff’s 50.8, and passes for 0.246 EPA per play. They sit as the league’s best third-down offense and a top-ten red-zone unit by touchdown rate. Week one already gave us a glimpse; Green Bay handled Detroit 27–13 and controlled the pace at Lambeau. If Love spits out explosives against Cover Three and Cover Four again, the total can sail past the high forties. Recent form pushes back, though, especially on Green Bay’s side of the ball. Over the last three games they’re at 19 points and 281.7 yards, barely 4.6 yards per snap. Detroit’s defense has leaked more yardage lately, but still allows only about 22 points and 5.5 yards per play. Green Bay’s defense trends the opposite way, giving up 12 points per game across that same stretch. When the freshest sample screams “tight, defensive tilt,” I respect it more than Love’s shiny season EPA line.

Strip it to back-of-envelope math and the picture still tilts under. Detroit scores 29.6 and allows 22.1; Green Bay scores 23.9 and allows 18.4. If you just average each offense with the opposing defense, you land around 24–23 for Detroit and Green Bay. That pushes a neutral projection near 47, already under the 48.5 hanging. Both offenses also do most of their work in the twenties, not the thirties. Neither profile screams habitual shootout, especially with both defenses top ten in yards per play allowed. The number looks like it’s assuming ceiling efficiency from both quarterbacks at once, which rarely shows up.

Packers vs. Lions pick, best bet

The market hangs Lions minus 2.5 at heavier juice, Packers plus 2.5, total parked at 48.5. That spread feels close to right; Detroit grades slightly better overall, but Green Bay owns the clear quarterback edge. Where the number looks stretched is the total, which prices something like 27–22 as the median environment. These teams combine to allow about 40 points per game, and both red-zone defenses sit in the stronger half. Detroit’s missing LaPorta and Joseph, thinning the explosive ceiling on both sides while pushing Campbell toward more conservative choices. Short week tendencies favor run volume, shorter route concepts, and fewer gadget shots, especially against Green Bay’s disciplined zones. This matchup feels more like a mid-forties total than something brushing fifty, even with both quarterbacks capable. I’m more willing to fade fireworks expectations than pick a thin side in a familiar divisional game. My primary position is under 48.5, with any Lions side action staying smaller and more speculative.

I expect Detroit to lean on Gibbs and Montgomery early, testing Green Bay’s front with duo and inside zone. They should live in eleven personnel without LaPorta, using Amon-Ra St. Brown as the motion engine against zone. Those crossers and options chew clock, move chains, and keep Rashan Gary from ruining possessions with splash plays. On the other sideline, Matt LaFleur should answer with his own heavy eleven usage and a patient Jacobs running plan. Love will get chances against Detroit’s man looks, but constant pressure should turn a few promising drives into punts. Both defenses tighten near the goal line, so I expect more field goals than your fantasy lineups would prefer. The most likely picture is physical, slightly ugly, and decided by one late drive rather than a barrage of explosives.

I land at Lions 23, Packers 20, with the under doing the heavy lifting on the ticket.

Best bet: Lions vs. Packers u48.5 total points (-105)

Tail it with me in the DKN Betting Group here!

For a prop lean, I’d rather ride Jahmyr Gibbs’ touches than chase a thin receiver ladder. Jahmyr Gibbs 70+ rushing yards at -120 is my favorite correlate to the under, and I’d play it to about -130. He’s sitting at 6.1 yards per carry with 951 rushing yards and owns just over half of Detroit’s carries, so volume plus efficiency are both on our side. Green Bay’s run defense looks stout in raw yards, but lives closer to middle of the pack by success rate, which invites Campbell to keep the ball on the ground. With LaPorta out and the Packers living in soft zone on early downs, Gibbs should see a steady diet of duo and inside zone. In a game where I expect Detroit to lean on ball control and both defenses to tighten in the red area, I’m happy to let Gibbs grind us to 70 and help the under along.

Best prop lean: Jahmyr Gibbs 70+ rushing yards (-120)

Tail it with me in the DKN Betting Group here!

Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.