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Chelsea vs. Barcelona prediction, pick for Tuesday 11/25/25

Chelsea vs. Barcelona prediction, pick for Tuesday 11/25/25

Published:

By: Ciaran Doyle

The 2025/26 UCL league phase continues on Tuesday as Chelsea host Barcelona in arguably the best game of the day.

The Blues are slight +135 favorites on DraftKings Sportsbook for this one, with a draw available at +300. Fancy a Barcelona win? The Spanish side are +170 on the moneyline.

Chelsea vs. Barcelona Prediction, Pick

This game could go either way, so I will take the over instead.

Both teams have seven points from their first four games, winning two, drawing one and losing one. Barcelona have scored 12 and conceded seven. Chelsea have scored nine and conceded six. Both teams sit in second place in their respective league tables. There isn’t much to separate these teams. I would give Barcelona the edge in quality, but with the game being in London, it’s a coin flip in my opinion.

There are goals to be had in this one, as evidenced by the results of both teams so far in this season’s Champions League. For Barca, four or more goals have been scored in two of four games. In the two games that went under this total, three total goals were scored. For Chelsea, four or more goals have been scored in three of their four matches.

Both teams score a lot, both teams concede a lot. I have no idea what’s going to happen in this one, but I am fairly confident it will be an entertaining goal fest.

The Pick: Over 3.5 Total Goals (-105)

Ciaran has been an editor for the DraftKings Network team since 2023. He graduated from the University of Arizona before attending Arizona State University for his master’s degree in sports journalism. Ciaran previously covered Phoenix Rising FC for Cronkite News before joining DraftKings. He is passionate about sports betting, and his biggest focus has always been on the NFL and soccer. You can find him on X at @Ciaran_Doyle7.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is ciarandoyle77) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.