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Best NFL Week 12 Player Prop Bets for Sunday 11/23/25

Best NFL Week 12 Player Prop Bets for Sunday 11/23/25

Published:

By: Blake Krass

The 2025 NFL season rolls on to the Sunday slate of Week 12. There are plenty of ways to get in on the action. Here’s a look at my favorite player prop bets for this week’s schedule, all of which you can place on DraftKings Sportsbook.

Without further ado, here are three of the best player props for NFL Week 12.


NFL Week 12 Player Props

Travis Kelce Anytime TD (+135)

Travis Kelce has started to ramp up his productivity over the past few weeks. In his last three games, he is averaging over six catches per game for over 85 yards per game. He has also scored a touchdown in two of those three games, including last week in Denver. Kelce was a bit inconsistent over the first few games of the season, but he now looks like he will be at top form for the Chiefs’ playoff push. This is a massive game against the Colts for Kansas City. The Chiefs are desperate for a win, and they will lean on their future Hall-of-Fame tight end to get them the win.

The Colts are one of the worst teams in the NFL at defending tight ends. They are allowing 72.6 receiving yards per game to opposing tight ends, the second-most in the league this season. The Colts are a good defensive team, but 66% of the touchdowns they have allowed this season have come through the air. Whenever the Chiefs get into scoring position, they will put their faith in Patrick Mahomes to get the ball into the end zone, rather than running the ball. The Colts have struggled to stop the tight end all season, and Patrick Mahomes has looked to his favorite target with regularity in the red zone in recent weeks. Kelce has a great chance to score against the Colts as the Chiefs look for a big win.

Andrei Iosivas Over 35.5 Receiving Yards (-114)

The Bengals will be without Ja’Marr Chase this week against the Patriots as he serves a suspension. That hurts the Bengals’ offense significantly, and they will need other players to step up. Tee Higgins will be elevated to the WR1 role, which means he will be blanketed by Patriots star cornerback Christian Gonzalez for most of this game. Gonzalez would typically be tasked with slowing down Chase, but he can now focus on Higgins instead. That means somebody below Higgins on the depth chart needs to perform, and Andrei Iosivas is the perfect candidate to do so.

Andrei Iosivas showed a lot of potential as a young receiver last season. However, he has been very inconsistent this season and is missing Joe Burrow at quarterback. Over the last two weeks, he has been more involved in the offense, totaling 11 targets. In this game, the Bengals need him to be a real threat. It is nearly impossible to run against the Patriots. That unit ranks fifth in the NFL in defensive EPA/rush. Joe Flacco will need to be productive through the air for the Bengals to move it. With Chase out and Higgins being hounded by Gonzalez, Iosivas should get plenty of targets. He should take this opportunity and create some big plays for Cincinnati, getting over this receiving yards number.

Darnell Mooney Longest Reception o19.5 Yards (-120)

Darnell Mooney is another receiver who needs to step up this week. Mooney was dealing with injuries throughout the first few weeks of the season, causing him to miss time and have minimal impact when he did play. Even since returning to the field, he has struggled to look like the guy who had a breakout 2024 season. Drake London has dominated targets and done it all for the Falcons through the air this season. However, London is set to miss this game with an injury. That means Mooney will be the go-to guy for Kirk Cousins.

The Saints’ defense ranks 25th in the NFL in defensive EPA/dropback, so Cousins should be able to hit a couple of deep balls in this game. Cousins’ mobility and sharpness are issues. However, Cousins still has the arm to hit throws down the field when given time. While Mooney has been inconsistent, he is always dangerous with the ball in his hands. He had a 20-yard catch last week against the Panthers, his third 20+ yard catch of the season. Against the Saints, Cousins will look to hit another deep ball to Mooney. He should be able to make it two straight weeks with a catch of at least 20 yards due to the number of targets he will be getting.

Blake Krass has contributed to DraftKings since 2024, and is a content creator with a specialty in sports betting. Blake primarily focuses on college football and NFL coverage but will also be covering college basketball, the NBA, MLB and more. Prior to arriving at DK, Blake was a sports betting writer for The Action Network.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.