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Houston Cougars vs. TCU Horned Frogs prediction, pick for CFB Week 13 on Saturday 11/22/25

Houston Cougars vs. TCU Horned Frogs prediction, pick for CFB Week 13 on Saturday 11/22/25

Published:

By: Dan Johnson

Tiger Stadium gets weird in November when the stakes are more pride than banners. LSU walks in 6–4 with an interim coach, a top-20 scoring defense, and an offense still trying to remember what explosive felt like. Western Kentucky shows up 8–2 with an Air Raid label, a 31.5-points-per-game resume, and zero Power Four data points. It’s SEC athletes versus C-USA timing, and the board is daring you to believe the gap isn’t as big as the helmets. The question is less who wins? than how violent does the math get? Below is my prediction for CFB Week 13’s football game between the Houston Cougars and the TCU Horned Frogs.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Houston vs. TCU prediction, preview

TCU wants this game in Hoover’s right arm. Quarterback Josh Hoover sits near 2,900 yards with 23 touchdowns, pushing an offense at 6.1 yards per snap and almost 300 passing yards per night. Eric McAlister has lived like a Biletnikoff semifinalist, around 95 receiving yards per game with eight scores and real vertical teeth, while Jordan Dwyer gives them a second true chain-mover. The problem is texture, not talent: the Frogs run for only about 122 yards per game at 3.8 per carry, and injuries behind them thin what little balance exists. Houston’s defense quietly ranks top-40 in yards per play allowed, top-10 in fewest passes of ten-plus yards, and holds opponents near 3.7 per carry. If the Cougars keep explosive shots in front and force Hoover to string twelve-play drives, TCU’s one-dimensional lean becomes a liability instead of a weapon.

Houston’s offense looks less loud but more complete on tape. Quarterback Conner Weigman brings about 2,100 passing yards at 7.9 per attempt plus over 400 rushing yards and nine rushing scores, which matters against a TCU front that tackles well but leaks explosives through the air. Dean Connors has 725 rushing yards and six total touchdowns on 4.6 per carry, with passing-down utility that keeps Houston versatile on third and medium. Tight end Tanner Koziol and receiver Amare Thomas split the middle and outside, combining for over 1,300 yards and thirteen touchdowns, giving Weigman easy answers versus pressure and a real vertical trigger. TCU’s defense allows 26.5 points and 374 yards per game, only 3.4 per rush but 247 through the air, and they sit in the hundreds nationally in explosive passes allowed while letting opponents score on roughly nine of ten red-zone trips. That combination—stout early, shaky late—pairs badly with a Cougar attack that cashes about 94% of its red-zone possessions.

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TCU vs. Houston pick, best bet

The best TCU case lives in variance and schedule. Hoover has shown real ceiling, and this pass game can absolutely drop thirty when protection holds and McAlister wins early downs. The Frogs sit around 5.8–6.1 yards per snap and about 45% on third down, numbers that normally translate to better than 4–6 against a schedule with multiple bowl teams. Houston’s profile has some soft spots: their record leans on road wins, they are only modestly better than average in opponent third downs, and a rash of turnovers at UCF showed how quickly things wobble when Weigman presses. If Houston coughs it up and TCU finally turns air yards into clean explosives, grabbing the points looks sharp.

I still land on Houston. The Cougars are 7–3 against the number with a scoring margin that fits that story, while TCU is 4–6 against the spread and scoring barely more than they allow. Houston owns the clock by about three minutes per game, wins both points-per-play and red-zone efficiency, and plays at home here on a day that actually matters for their ranking and title chatter. TCU’s injuries at running back push them toward even more dropback volume into a secondary specifically built to erase deep shots, while Houston’s balanced run game and quarterback legs attack the exact stress points in TCU’s explosive-pass and red-zone numbers. I think this should sit closer to Houston -3 than a cheap -1.5, so I’m backing the Cougars to close strong.

I’ll take Houston 31, TCU 24, and lay the short number with Houston -1.5.

Best bet: Houston -1.5 (-110) vs. TCU

Tail it with me in the DKN Betting Group here!

Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.