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Fantasy College Football Picks: Top DraftKings Week 13 CFB DFS Targets, Values for 11/22/25

Fantasy College Football Picks: Top DraftKings Week 13 CFB DFS Targets, Values for 11/22/25

Published:

By: Blake Krass

College football Week 13 has many great games on the featured DFS slate this Saturday. You can play weekly DFS contests at DraftKings for the duration of the season.

DraftKings has a CFB $175K Saturday Kickoff contest, with $50,000 going to first place. You can enter the contest for just $20 here.

Quarterback

Stud

Julian Sayin, Ohio State vs. Rutgers, $8,900

Julian Sayin is one of the top Heisman contenders heading down the final stretch of the regular season. It took him a couple of weeks to gel with his superstar receivers, but he is now unstoppable. Ohio State leads the nation in EPA/dropback with Sayin throwing to Jeremiah Smith and Carnell Tate. Sayin now has a 25-4 TD-INT ratio on the season and ranks second in the nation in QBR. Rutgers ranks 117 nationally in defensive EPA/dropback, so this should be a chance for Sayin to put up some huge numbers.

Value

Noah Fifita, Arizona vs. Baylor, $6,400

Noah Fifita is one of the most experienced quarterbacks in college football. Since the start of the 2023 season, he has the seventh-most passing yards of any quarterback. This has arguably been the best season of his career. He is just two touchdowns away from setting a single-season career-high and is also on pace to have the fewest interceptions of his college tenure. Fifita ranks sixth in the nation in passing touchdowns and should keep the momentum going in this game against Baylor. The Bears rank 117th in the nation in defensive success rate and should struggle to get stops in this game.

Running Back

Stud

Noah Whittington, Oregon vs. USC, $7,100

Noah Whittington has been having a great season for Oregon. The Ducks pace the Big Ten in rushing this season, with Whittington leading the charge. Over his past four games, Whittington is averaging 103 rushing yards per game. This game against USC should be a big game for Whittington. The Trojans have one of the best offenses in the country, and the best way to stop them is to keep the ball out of QB Jayden Maiava’s hands. Oregon should try to run the ball and control the time of possession. USC’s defense has been much better against the pass this season, but it ranks 122nd in defensive rushing success rate. This will be a heavy usage game for Whittington, and he should follow through with big numbers.

Value

CJ Donaldson, Ohio State vs. Rutgers, $5,600

CJ Dondalson is one of the most unique running backs in the country. Most teams at the college level don’t have a dominant goal-line back like the Buckeyes do in Donaldson. Ohio State’s primary back, Bo Jackson, has 38 more carries and nearly 450 more yards than Donaldson does on the season. Despite that, Donaldson has nine rushing touchdowns, compared to just three for Jackson. Ohio State uses him as a true goal-line back, and the touchdowns have been plentiful this season. The Ohio State offense ranks tenth in the nation in EPA/rush, while the Rutgers defense ranks 109th in EPA/rush and 118th in rushing success rate. That should mean plenty of scoring opportunities for Donaldson by the goal line.

Wide Receiver

Stud

Skyler Bell, UConn vs. FAU, $7,400

Skyler Bell is one of the most underrated receivers in the country. He plays at UConn, so he doesn’t get the national attention that others get. However, he leads the nation in receptions and receiving touchdowns, and ranks second in receiving yards. Bell has great hands and tremendous speed to create big plays out of nowhere. The UConn and FAU passing attacks are two of the top-ten passing offenses in the country. That should make this a high-possession shootout, where Bell has plenty of chances to produce.

Value

Joseph Manjack IV, TCU vs. Houston, $4,400

If looking for one very cheap player with upside potential, Joseph Manjack is a solid choice. His snap rate is high, and he gets a few targets from Josh Hoover almost every week. Then he has a couple of games this season where he played a big role in the offense, like against Colorado and Arizona State. TCU would love to knock out its in-state rivals, who are still in Big 12 contention, so this should be a good effort from the Horned Frogs. Manjack has a solid floor with a high ceiling, making him a strong play at such a low price.

Flex/Superflex

You can use any of the other names I listed in the above categories for the flex or superflex positions. However, here are a few more names, just in case.

Stud

Joe Fagnano, QB, UConn vs. FAU, $8,500

Joe Fagnano is the distributor to Skyler Bell in this electric UConn offense. Fagnano ranks third in the nation in passing touchdowns and sixth in passing yards. Remarkably, Fagnano only has one interception on the season despite being immersed in such a pass-heavy offense. FAU ranks 109th in the nation in defensive EPA/dropback and 111th in defensive success rate. Fagnano should tear that defense apart and put up some massive numbers in this game.

Value

Seth McGowan, RB, Kentucky vs. Vanderbilt, $5,800

Seth McGowan has been a solid running back for Kentucky this season. Despite being an offense that has struggled mightily at times this year, he still ranks third in the SEC in rushing touchdowns (12). He has been especially on fire over the past two weeks. Against Florida and Tennessee Tech, McGowan combined for 164 yards and five touchdowns. He has multiple games with over 100 rushing yards this season and should produce against Vanderbilt. The Commodores rank 11th in the SEC in total defense and can be beaten down by good offenses. Kentucky might not be a great offense, but McGowan is a very good back and should get his stats against Vanderbilt.

Blake Krass has contributed to DraftKings since 2024, and is a content creator with a specialty in sports betting. Blake primarily focuses on college football and NFL coverage but will also be covering college basketball, the NBA, MLB and more. Prior to arriving at DK, Blake was a sports betting writer for The Action Network.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.