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Memphis Tigers vs. Wake Forest Demon Deacons prediction, pick for NCAAM on Friday 11/21/25

Memphis Tigers vs. Wake Forest Demon Deacons prediction, pick for NCAAM on Friday 11/21/25

Updated:

By: Julian Edlow

Memphis and Wake Forest both came up just short against two of the best teams in the country on Thursday. Memphis hung tough with Purdue for much of the game before losing by nine points, but covering the spread. Wake took Texas Tech right down to the wire, losing by a single point. Now the two meet on Friday night in the Bahamas.

Memphis vs. Wake Forest (Friday 7:00pm ET)

Both of these teams were completely over looked in the first round of this tournament at Baha Mar, pushing national contenders to their limits. For Memphis, it was the third consecutive loss, after opening the season with a win over San Francisco. While I don’t have too many reasons to fade the Tigers, the lineup does lack some star power. Dug McDaniel provides some senior leadership and experience at point guard, to go along with some good athletes around him.

That said, this Wake Forest team has played hungry to start the season, and is a team I want to be backing. Not only did the Demon Deacons take Texas Tech to the final possession just a day ago, but last week they pushed Michigan to the final possession, losing another one point game to a Top-10 team.

This is Wake’s time to breakthrough and collect a win. Juke Harris has broken out as a star for this team, and is surrounded by better talent and depth than the Memphis roster has to offer. This team has been on the cusp of a big upset multiple times this season, and this is where the Demon Deacons can let some of that out against an opponent they are better than.

Wake ranks significantly ahead of Memphis in both offensive and defensive efficiency, with the Demon Deacons ranking 28th on the defensive side of the ball. Expect them to put the Tigers into some scoring droughts and pull away in this game.

College Basketball Pick: Wake Forest -3 (-110)

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Julian Edlow has contributed to DraftKings since 2015, and is currently employed as a Content Specialist with a focus on Sports Betting. During his time at DK, Julian has experience covering the NFL, NBA, MLB, College Football and College Basketball. He has also has experience covering both Daily Fantasy Sports and Sportsbook as a writer and on-air talent. Prior to arriving at DK, Julian was a reporter covering the Boston Celtics and the NBA for multiple outlets. Julian is currently leading the charge on DK Network’s College Football and College Basketball coverage, although you’ll still find him contributing to NFL and NBA.
Disclaimer

All views expressed are my own. I am an employee of DraftKings and am ineligible to play in public DFS or DKSB contests.