Every week, DraftKings Network analysts share their favorite NFL bets on DraftKings Sportsbook for each NFL game.
Below is a collection of the top NFL best bets for Week 11 Sunday Night Football between the Eagles and Lions.
To see all DraftKings betting analysis, head over to the DraftKings Network sports betting picks page!
Check out the numerous NFL betting markets available on DraftKings Sportsbook!
Alex Hunter: Best Saquon Barkley prop bet
Saquon Barkley O 16.5 Carries (-132)
Read Alex’s full betting analysis here: Saquon Barkley best prop bet for Eagles vs. Lions on Sunday 11/16/25
Sean Barnard: Lions at Eagles Best Prop Bets
Saquon Barkley Over 70.5 Rushing Yards (-110)
Jahmyr Gibbs to Record 100+ Rushing & Receiving Yards (+130)
A.J. Brown Anytime Touchdown (+145)
Read Sean’s full betting analysis here: NFL Best Bets: Lions at Eagles Best Prop Bets on Sunday Night Football 11/16/25
Keagan Smith: Detroit Lions vs. Philadelphia Eagles prediction, pick
PHI Eagles over 23.5 points (-135)
Read Keagan’s full betting analysis here: Detroit Lions vs. Philadelphia Eagles prediction, pick for NFL Week 11 on Sunday 11/16/25