Week 10 of the 2025 NFL season continues with a great Monday Night Football game between the Philadelphia Eagles and the Green Bay Packers. There are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this season is Pick6 Fantasy Football!
Here are my top Pick6 plays for Week 10 Monday Night Football.
Jalen Hurts More than 0.5 Rush + Receiving Touchdowns
Jalen Hurts has been a rushing touchdown machine over the past several seasons. Since the start of the 2023 regular season, Jalen Hurts leads the NFL in rushing touchdowns. Including the postseason, Hurts has a remarkable 57 rushing touchdowns in 63 games played. Hurts has scored plenty of “tush push” touchdowns, but can also score on designed runs or scrambles. The Eagles’ offense has been shaky over the past few weeks, so following last week’s bye week, Philadelphia should have some fresh looks implemented. Over the first four games of the season, Hurts was averaging over ten carries per game and had four rushing touchdowns. In his last four games, Hurts is averaging just over four carries per game and has only one rushing touchdown. The Eagles should have worked in the bye week to get back to what was effective earlier in the season. Green Bay’s defense ranks eighth in dropback success rate, but 19th in rushing success rate. There should be a healthy dose of Hurts using his legs in this game, which often results in a Hurts rushing score.
Luke Musgrave More Than 30.5 Receiving Yards
Luke Musgrave is going to play a huge role in the Packers’ offense the rest of the season. Tucker Kraft is out for the rest of the season, making Musgrave the new TE1 in Green Bay. Musgrave might not be on Tucker Kraft’s level as a receiver, but he should still succeed in such a crisp offensive system. Matt LaFleur is a great offensive coach and Green Bay leads the NFL in offensive EPA/dropback. This passing offense has been phenomenal this season and the tight end position plays a key role in making things click. Musgrave is in his third season with the Packers, so while he has been a backup, he knows the offense and his quarterback well. Even after stepping in for an injured Kraft for part of the game last week, Musgrave had three catches for 34 yards. Musgrave was a second-round pick in 2023 and has a lot of talent; he was just subjected to a minimal role in the offense because of how good Kraft has been. This is Musgrave’s chance to prove himself as a viable NFL tight end and he should rise to the occasion. The Eagles rank 18th in defensive EPA/dropback, so Jordan Love should work it through the air on Monday night. Musgrave should clear this number for the second straight game.
Saquon Barkley Less Than 77.5 Rushing Yards
Saquon Barkley is having a quiet season, especially compared to his record-breaking 2024-25 season. After rushing for over 2,000 yards last season, Barkley has just 519 yards so far this season, ranking 16th in the NFL in rushing yards. He has been used more in the passing game this season than he was last season. Teams are refusing to let Barkley beat them on the ground like he did against almost everybody last season. The struggles in the passing game for the Eagles are encouraging opposing defenses to sell out to stop the run and force Jalen Hurts to beat them with his arm. Barkley has only had over 77.5 rushing yards in two games all season, one of them last time out against the Giants. Against New York, Barkley finally broke one long run for 65 yards. Prior to that game, he didn’t have a run of longer than 18 yards all season. If the Packers can just stop him from breaking off a long run like he did in that game, they should keep him under this rushing total.
What is DraftKings Pick6?
Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.
How to Play
Create a Pick Set
Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice, and you must pick players from at least two different teams.
Enter an Amount
Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.
Sweat Your Picks
When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.
Compete for Prizes
Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.
Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!
