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Best Anthony Davis prop bets for Mavericks vs. Spurs on Wednesday 10/22/25

Best Anthony Davis prop bets for Mavericks vs. Spurs on Wednesday 10/22/25

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By: Keagan Smith

After a thrilling doubleheader on Opening Night, the NBA action continues on Wednesday! A Texas-sized showdown between the Dallas Mavericks and San Antonio Spurs sees dueling big men as well as the debut of a prized No. 1 pick, so this matchup looks like one of the top options on tonight’s 12-game slate. With that in mind, we’re getting into player prop bets for betting cards.

Here are the top Anthony Davis prop bets on DraftKings Sportsbook for Mavericks vs. Spurs on Wednesday night.

Best Anthony Davis prop bets on DraftKings Sportsbook

The move that sent Anthony Davis to the Mavericks this past February quickly became the trade heard ’round the world. Luka Doncic departed Dallas in that deal, which set the Mavs up with a top-tier big man to complement a roster which was still geared to compete in the Western Conference, albeit with a different look. However, Davis struggled with injuries and the team cratered down the stretch after a season-ender to Kyrie Irving as well. Now fully healthy, he’s ready to make some noise alongside No. 1 pick Cooper Flagg, who will start at point guard tonight.

Davis posted some very impressive numbers when healthy last season and emerged as the primary option for the Los Angeles Lakers prior to the trade, then did the same for Dallas. Over the full campaign, the big man averaged 24.7 points with 11.6 rebounds and 3.5 assists, all despite his shooting efficiency cratering to career-worst marks once he joined the Mavs (likely due to health-related reasons). Davis has now enjoyed a full offseason to get his body right and should be ready to go int he season opener.

The superstar center’s prop bet lines on DraftKings Sportsbook sit at 24.5 points, 10.5 rebounds, 3.5 assists, 1.5 blocks and 1.5 steals. His combined PTS + REB + AST line comes in at 39.5.

Tonight brings a difficult matchup for the Mavericks’ offense as they face Victor Wembanyama and the Spurs. The young center missed the second half of last season but is once again healthy and every bit of the league-changing defender he showed prior to his absence. He’s an unbelievable talent who can create problems with his length in the paint, so one may assume Davis faces a real challenge. When digging deeper into the stats though, Davis has averaged 30.8 points and 12.4 rebounds in five games against Wembanyama in his career. In three meetings last season, Davis also scored 40, 19, and 30 points while hauling in 12, 14, and 13 rebounds.

Granted, all of those games came with the Lakers rather than the Mavericks. Still, Davis’ size and strength are enough to battle with Wembanyama down low and potentially provide an edge. Over 24.5 points and over 10.5 rebounds both feel quite obtainable, but the scoring prop may be the better call since Davis will play the four alongside Dereck Lively II at center tonight. With that in mind, we’re going over on that one.

Best bet: Anthony Davis over 24.5 points (-106)

Keagan is a Texas-based editor and analyst who believes sports are the true eighth wonder of the world. After starting out in local media, he’s provided coverage for DraftKings Network since 2024. He gravitates toward football, hoops and hockey, but is happy to watch and write about any game that involves a ball or a puck. While his own athletic career ended in middle school, he’s also an avid fantasy player with a soft spot for dynasty formats, spending countless hours crafting the ever-elusive perfect squad.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.