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Eintracht Frankfurt vs. Liverpool prediction, pick for Wednesday 10/22/25

Eintracht Frankfurt vs. Liverpool prediction, pick for Wednesday 10/22/25

Published:

By: Ciaran Doyle

The 2025/26 UCL league phase continues on Wednesday as Eintracht Frankfurt and Liverpool will face each other in Germany.

Liverpool are -170 favorites on DraftKings Sportsbook for this one, with a draw available at +380. Fancy a Frankfurt upset? The German side is +380 on the moneyline.

Eintracht Frankfurt vs. Liverpool Prediction, Pick

This bet can be found under the “Match Parlays” tab. Both teams have had inconsistent starts to their Champions League campaigns, each recording one win and one loss in their first two matches. The consistent theme across those games is goals galore.

Let’s start with Frankfurt. It was a dream start to their UCL league phase, beating Galatasaray 5-1 at home. They were then brought back to reality, losing 5-1 to Atlético Madrid in Spain.

Funnily enough, Liverpool have faced the same two teams to start the league phase. They beat Atlético 3-2 at home in their opening match before losing 1-0 away to the Turkish side.

In three of the four games these sides have played in, over 1.5 goals have easily been scored.

Next, we get to Liverpool winning this one. Yes, they are on a four-game losing streak in all competitions, but that won’t last forever. Wednesday’s game feels like the perfect get-right spot for the reigning English champions. Frankfurt aren’t exactly red hot at the moment, as they are winless in their last three games, including a 5-1 loss to Atlético, a 3-0 loss to Bayern Munich and most recently a 2-2 draw with SC Freiburg.

Expect the Reds to get back on track in this one. They will have all the motivation in the world to not only win this, but also put in a great performance while doing so. A dominant performance will certainly quieten the noise around the team at the moment, which has got very loud, very quickly.

The Pick: Liverpool win and Over 1.5 Total Goals (-150)

Ciaran has been an editor for the DraftKings Network team since 2023. He graduated from the University of Arizona before attending Arizona State University for his master’s degree in sports journalism. Ciaran previously covered Phoenix Rising FC for Cronkite News before joining DraftKings. He is passionate about sports betting, and his biggest focus has always been on the NFL and soccer. You can find him on X at @Ciaran_Doyle7.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is ciarandoyle77) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.