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Top DraftKings Pick6 NFL Picks: Most Popular Plays from Week 6

Top DraftKings Pick6 NFL Picks: Most Popular Plays from Week 6

DraftKings Fantasy Advice Pick6 NFL

Published:

By: Sam Connon

With Sunday in the rear-view mirror, another DraftKings Pick6 contest has come and gone. Whether the NFL players themselves came in above or below their projected lines, there were winners on all sides.

Every week, we’ll be taking a look at which players and plays helped the most NFL Pick6 lineups. The Sunday night showdown between the Kansas City Chiefs and Detroit Lions drew plenty of attention, as stars on both sides stood out with popular picks. As for the main slate, Christian McCaffrey and Jonathan Taylor continued to make customers proud.

Here were the biggest draws and drivers for big-time payouts over the course of Week 6:

  1. QB Patrick Mahomes (KC)
  2. RB Jahmyr Gibbs (DET)
  3. WR Amon-Ra St. Brown (DET)
  4. RB Christian McCaffrey (SF)
  5. QB Jared Goff (DET)
  6. TE Travis Kelce (KC)
  7. RB Josh Jacobs (GB)
  8. WR Xavier Worthy (KC)
  9. RB David Montgomery (DET)
  10. WR Emeka Egbuka (TB)

10 NFL Players Who Drove the Most Payout in Week 6 on Pick6

  1. QB Patrick Mahomes (KC)
  2. RB Josh Jacobs (GB)
  3. RB Christian McCaffrey (SF)
  4. QB Jared Goff (DET)
  5. WR Sterling Shepard (TB)
  6. TE Travis Kelce (KC)
  7. WR Emeka Egbuka (TB)
  8. WR Amon-Ra St. Brown (DET)
  9. WR Ja’Marr Chase (CIN)
  10. QB Jordan Love (GB)
  1. Amon-Ra St. Brown MORE Receiving Yards (INCORRECT)
  2. Tyquan Thornton MORE Receiving Yards (INCORRECT)
  3. Emeka Egbuka MORE Receiving Yards (INCORRECT)
  4. Jonathan Taylor MORE Rushing + Receiving Touchdowns (CORRECT)
  5. Travis Kelce MORE Receiving Yards (CORRECT)
  6. Jahmyr Gibbs MORE Rushing + Receiving Touchdowns (INCORRECT)
  7. Jared Goff MORE Passing Yards (INCORRECT)
  8. Josh Jacobs MORE Rushing + Receiving Touchdowns (CORRECT)
  9. Javonte WIlliams MORE Rushing + Receiving Touchdowns (INCORRECT)
  10. Kareem Hunt MORE Rushing Yards (INCORRECT)

10 Week 6 NFL Pick6 Picks That Drove the Most Payout

  1. Sterling Shepard LESS Receptions
  2. Matthew Stafford LESS Completions
  3. Travis Etienne Jr. LESS Rush Attempts
  4. Christian McCaffrey MORE Receiving Yards
  5. Josh Jacobs MORE Rushing + Receiving Touchdowns
  6. Travis Kelce MORE Receiving Yards
  7. Patrick Mahomes LESS Passing Yards
  8. Christian McCaffrey MORE Rushing + Receiving Touchdowns
  9. Isiah Pacheco MORE Rushing Yards
  10. Baker Mayfield MORE Passing Yards

Sam Connon
Sam joined DraftKings in 2025 following five years with Sports Illustrated’s “On SI” network. He has covered the UCLA Bruins, New England Patriots, Tampa Bay Rays, MLB, MiLB and NBA, on top of earning awards from the Society of Professional Journalists and College Media Association during his time as a student at UCLA.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.