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Top DraftKings DFS Picks: Most Valuable Players from NFL Week 6

Top DraftKings DFS Picks: Most Valuable Players from NFL Week 6

DraftKings Fantasy Advice DFS NFL

Published:

By: Sam Connon

The 2025 NFL season is in full swing, so DraftKings customers everywhere are diving head-first into all the action.

Every week, we’ll be taking a look at which players appeared in the most DraftKings DFS lineups, as well as the ones who had the biggest role in wins. Rico Dowdle was a popular pick to repeat his dominant showing from Week 5, and he did just that. Jacoby Brissett and Drake Maye, who shared a quarterback room in 2024, powered a handful of Arizona Cardinals and New England Patriots pass-catchers to big games, creating some unexpected value for thousands of cunning customers.

Here is some exclusive data behind the biggest drivers of DraftKings DFS winnings from the NFL’s Week 6 main slate:

Highest Ownership Entry

These players appeared in lineups the most often.

  1. RB Rico Dowdle (CAR)
  2. WR Puka Nacua (LAR)
  3. RB Javonte Williams (DAL)
  4. RB Rachaad White (TB)
  5. RB Josh Jacobs (GB)
  6. WR Jaxon Smith-Njigba (SEA)
  7. RB Christian McCaffrey (SF)
  8. RB Kyren Williams (LAR)
  9. WR Emeka Egbuka (TB)
  10. WR Tetairoa McMillan (CAR)

Most Valuable Players

These players scored the most points relative to their salary.

  1. WR Kayshon Boutte (NE)
  2. RB Rico Dowdle (CAR)
  3. QB Jacoby Brissett (ARI)
  4. WR Kameron Johnson (TB)
  5. WR Michael Mayer (LV)
  6. RB Kimani Vidal (LAC)
  7. WR George Pickens (DAL)
  8. TE Oronde Gadsden II (LAC)
  9. WR DeMario Douglas (NE)
  10. TE Tyler Higbee (LAR)

Most Valuable Stacks

These pairs of teammates scored the most points relative to their combined salaries.

  1. QB Drake Maye & WR Kayshon Boutte (NE)
  2. QB Bryce Young & RB Rico Dowdle (CAR)
  3. QB Jacoby Brissett & WR Zay Jones (ARI)
  4. QB Jacoby Brissett & WR Greg Dortch (ARI)
  5. QB Jacoby Brissett & TE Trey McBride (ARI)
  6. QB Drake Maye & WR DeMario Douglas (NE)
  7. QB Joe Flacco & TE Tanner Hudson (CIN)
  8. QB Jacoby Brissett & TE Elijah Higgins (ARI)
  9. QB Jacoby Brissett & WR Michael Wilson (ARI)
  10. QB Jacoby Brissett & RB Zonovan Knight (ARI)

Players With Highest Winning Lineup Concentration

Out of all winning lineups, these players appeared the most often.

  1. RB Rico Dowdle (CAR)
  2. WR Jaxon Smith-Njigba (SEA)
  3. RB Rachaad White (TB)
  4. RB Josh Jacobs (GB)
  5. WR Chris Olave (NO)
  6. WR Ladd McConkey (LAC)
  7. RB Javonte Williams (DAL)
  8. QB Trevor Lawrence (JAX)
  9. WR Tetairoa McMillan (CAR)
  10. WR Puka Nacua (LAR)

Players With Highest Winning Entry Percentage

Out of all lineups, lineups that included these players won money the most often.

  1. TE Michael Mayer (LV)
  2. WR George Pickens (DAL)
  3. WR Jaxon Smith-Njigba (SEA)
  4. QB Trevor Lawrence (JAX)
  5. WR Kayshon Boutte (NE)
  6. RB Rico Dowdle (CAR)
  7. WR Brian Thomas Jr. (JAX)
  8. WR Ladd McConkey (LAC)
  9. WR Chris Olave (NO)
  10. QB Jacoby Brissett (ARI)

*For purposes of this data, DST were not considered to be “players”

Sam Connon
Sam joined DraftKings in 2025 following five years with Sports Illustrated’s “On SI” network. He has covered the UCLA Bruins, New England Patriots, Tampa Bay Rays, MLB, MiLB and NBA, on top of earning awards from the Society of Professional Journalists and College Media Association during his time as a student at UCLA.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.