The Bills picked up their first loss last week to the Patriots and will now play the Falcons, who are coming off their bye week.
This is one of two Monday Night Football games in Week 6.
Buffalo is a 4.5-point favorite and -205 on the moneyline, while Atlanta is +170 on DraftKings Sportsbook. The points total is set at 49.5.
Here are my top Josh Allen prop bets for Monday’s game between the Bills and Falcons.
Best Josh Allen Prop Bets on DraftKings Sportsbook
No matter the game, opponent, start time or location, Allen is the focal point of the Bills’ offense. He won his first MVP last season and is playing up to those standards once again in 2025.
The 29-year-old has 1,217 yards, nine touchdowns and two interceptions on a 70.4 percent completion rate. He threw for at least two touchdowns in four of five games, with the exception being a 30-10 blowout of the Jets.
Allen is also an impressive runner, totaling 212 yards and three touchdowns on 40 carries. Whether he’s in the pocket or scrambling, he’s a threat to defenses.
Buffalo and Allen may face some resistance this week against a stout Falcons defense. Atlanta allows the least amount of overall and passing yards. The rushing defense is weaker, allowing the 16th fewest yards, however.
This is where there may be some openings. James Cook will get the bulk of the carries, but Allen should get some redzone opportunities, too. Atlanta allows the seventh fewest rushing touchdowns, but the tandem of Cook and Allen might be the best in the NFL.
Selling out for Cook could leave Allen with an easy lane to score a touchdown. His anytime touchdown prop is listed at -105, but his first touchdown prop is at +500. Both are good Monday Night Football bets.