Week 6 of the 2025-26 NFL season continues with a great Sunday Night Football matchup between the Kansas City Chiefs and the Detroit Lions. There are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this season is Pick6 Fantasy Football!
Here are my top Pick6 plays for Sunday Night Football.
Kareem Hunt More Than 0.5 Rushing + Receiving TDs
Kareem Hunt has been the Chiefs’ primary rusher this season, not counting Patrick Mahomes. Hunt came off the couch last season to carry the ball for the Chiefs after Isiah Pacheco’s injury. However, Pacheco was never able to get back up to full speed, causing the Chiefs to turn back to Hunt during their run to the Super Bowl. Even after having all offseason to recover, Pacheco is not back to his old self. It has been a pretty even split between Pacheco and Hunt, but Hunt has slightly more rush attempts and yards. Where the difference has been most apparent, however, is at the goal line. Hunt has three rushing touchdowns on the season, while Pacheco is yet to score on the ground. There is an even balance between the two backs for most of the game, but Hunt is getting better scoring chances. That should allow him to find the end zone in this big game against the Lions.

David Montgomery More Than 43.5 Rushing Yards
Speaking of running back duos, David Montgomery is one half of the best running back duo in the NFL. Jahmyr Gibbs and David Montgomery, also known as Sonic and Knuckles, have been a key part of the fantastic Lions’ offense the past several years. The Lions got dominated by the Packers in Week 1, but over their past four games, they rank first in the NFL in offensive EPA/play. Detroit’s offense looks fantastic, and they should move the ball against the Chiefs. The Chiefs have been awful at stopping the run. They rank 31st in the NFL in defensive EPA/rush and 30th in defensive rushing success rate. The Lions should lean on their run game to control the clock and keep Patrick Mahomes off the field. Montgomery is averaging 62 rushing yards per game this season and should get over this number against the Chiefs.

Patrick Mahomes More Than 29.5 Rushing Yards
Patrick Mahomes has been the Chiefs’ leading rusher this season. Kareem Hunt is a great goal-line back, but he lacks explosiveness. Meanwhile, Isiah Pacheco has been unable to get any of his old explosiveness back. Patrick Mahomes is dropping back on a huge percentage of offensive plays, but is using his legs more often than he normally would in the regular season. Mahomes used to save his legs for the playoffs, but the Chiefs have needed him to run to keep the chains moving. Mahomes is averaging 38 rushing yards per game this season. This Lions defense is tough to beat, ranking in the top five in the NFL in defensive EPA/rush and defensive success rate. The Chiefs will struggle to move the ball, which means they likely need Mahomes to use his legs once more. There will be plenty of dropbacks where Mahomes has nobody open and should take off and run. That should lead to him getting over this number once again.

What is DraftKings Pick6?
Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.
How to Play
Create a Pick Set
Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice, and you must pick players from at least two different teams.
Enter an Amount
Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.
Sweat Your Picks
When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.
Compete for Prizes
Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.
Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!