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Boston Bruins vs. Buffalo Sabres Prediction, Pick for Saturday 10/11/25

Boston Bruins vs. Buffalo Sabres Prediction, Pick for Saturday 10/11/25

Published:

By: Charlie Cummings

Now that NHL regular season action is underway, we’re starting to get a good idea of what these teams look like. The Boston Bruins (2-0) have impressed in the early going, while the Buffalo Sabres (0-1) have disappointed. Will those trends continue on Saturday, or will these Eastern Conference rivals switch it up?

The Bruins have a slight edge at -115 on the moneyline on DraftKings Sportsbook, while the Sabres are listed at -105. The total is set at 5.5 goals. Let’s get into a preview, prediction, and pick for this opening night matchup between the Sabres and Bruins.


Sabres vs. Bruins Preview

Last year was a rough one for Boston. Their usual excellence collapsed in jarring fashion, turning a perennial contender into a deadline seller. The hope is that some internal development and stability can get them back into the playoff mix — and so far this season, they’ve looked good. Boston won their first two games, including an electrifying overtime win against the Chicago Blackhawks in the second half of a back-to-back.

Meanwhile, it was the same old for the Sabres in their first game. After being one of the worst defenses in the league last year, nothing looked much different in their 4-0 loss to the New York Rangers. Despite the presence of Rasmus Dahlin and Owen Power on the blue line, the defense doesn’t look strong. Meanwhile, the offense is lacking outside of Tage Thompson. It could be another long year in upstate New York.

Sabres vs. Bruins Prediction, Pick

There is talent on the Sabres, without a doubt. But the Bruins looked pretty convincing in their first two games and should at least be a fringe playoff contender if things keep up. I can’t say the same for the Sabres. Count on Boston to make it three in a row to open the season.

Best Bet: Boston Bruins Moneyline -115

Charlie Cummings is a Bay Area-born writer living in Denver. A basketball junkie, he specializes in NBA and WNBA content, but also dabbles in soccer, baseball, football and hockey. You can find him on Twitter @klaytheist11 where he’s posting through it on a daily basis.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.