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Top DraftKings DFS Picks: Most Valuable Players from NFL Week 4

Top DraftKings DFS Picks: Most Valuable Players from NFL Week 4

DraftKings Fantasy Advice DFS NFL

Published:

By: Sam Connon

The 2025 NFL season is in full swing, so DraftKings players everywhere are diving head-first into all the action.

Every week, we’ll be taking a look at which players appeared in the most DraftKings DFS lineups, as well as the ones who had the biggest role in wins. A trio of rookie running backs headlined the long list of winners on Sunday, all while high-priced stars like Puka Nacua and James Cook III left customers satisfied too.

Here is some exclusive data behind the biggest drivers of DraftKings DFS winnings from the NFL’s Week 4 main slate:

Highest Ownership Entry

These players appeared in lineups the most often.

  1. WR Puka Nacua (LAR)
  2. RB Omarion Hampton (LAC)
  3. RB James Cook III (BUF)
  4. RB Christian McCaffrey (SF)
  5. WR Jakobi Meyers (LV)
  6. WR Rome Odunze (CHI)
  7. WR Chris Olave (NO)
  8. RB Cam Skattebo (NYG)
  9. WR Tre Tucker (LV)
  10. WR Kennan Allen (LAC)

Most Valuable Players

These players scored the most points relative to their salary.

  1. RB Woody Marks (HOU)
  2. RB Justice Hill (BAL)
  3. RB Ashton Jeanty (LV)
  4. TE Tommy Tremble (CAR)
  5. WR Tutu Atwell (LAR)
  6. RB Omarion Hampton (LAC)
  7. QB Matthew Stafford (LAR)
  8. TE Dallas Goedert (PHI)
  9. TE Kyle Pitts Sr. (ATL)
  10. WR Puka Nacua (LAR)

Most Valuable Stacks

These pairs of teammates scored the most points relative to their combined salaries.

  1. QB Matthew Stafford & WR Tutu Atwell (LAR)
  2. QB Matthew Stafford & WR Puka Nacua (LAR)
  3. QB C.J. Stroud & RB Woody Marks (HOU)
  4. QB Michael Penix Jr. & WR Drake London (ATL)
  5. QB Michael Penix Jr. & TE Kyle Pitts (ATL)
  6. QB Geno Smith & RB Ashton Jeanty (LV)
  7. QB Drake Maye & WR Stefon Diggs (NE)
  8. QB Brock Purdy & TE Jake Tonges (SF)
  9. QB Patrick Mahomes WR & JuJu Smith-Schuster (KC)
  10. QB Jaxson Dart & TE Theo Johnson (NYG)

Players With Highest Winning Lineup Concentration

Out of all winning lineups, these players appeared the most often.

  1. WR Puka Nacua (LAR)
  2. RB Omarion Hampton (LAC)
  3. RB James Cook III (BUF)
  4. RB Christian McCaffrey (SF)
  5. WR Jakobi Meyers (LV)
  6. WR Chris Olave (NO)
  7. WR Drake London (ATL)
  8. RB Ashton Jeanty (LV)
  9. TE Tyler Warren (IND)
  10. TE Brenton Strange (JAX)

Players With Highest Winning Entry Percentage

Out of all lineups, lineups that included these players won money the most often.

  1. QB Matthew Stafford (LAR)
  2. QB Michael Penix Jr. (ATL)
  3. TE Brenton Strange (JAX)
  4. QB Jaxson Dart (NYG)
  5. RB Woody Marks (HOU)
  6. RB Ashton Jeanty (LV)
  7. WR Puka Nacua (LAR)
  8. QB Drake Maye (NE)
  9. RB Omarion Hampton (LAC)
  10. WR Drake London (ATL)

*For purposes of this data, DST were not considered to be “players”

Sam Connon
Sam joined DraftKings in 2025 following five years with Sports Illustrated’s “On SI” network. He has covered the UCLA Bruins, New England Patriots, Tampa Bay Rays, MLB, MiLB and NBA, on top of earning awards from the Society of Professional Journalists and College Media Association during his time as a student at UCLA.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.