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What happened to Miles Sanders? Live injury updates for NFL Week 4 on 9/28/25

What happened to Miles Sanders? Live injury updates for NFL Week 4 on 9/28/25

Published:

By: Ciaran Doyle

In the second quarter of Sunday’s game vs. the Packers, RB Miles Sanders exited the game with an ankle injury and is questionable to return.

Sanders rushed twice for eight yards and caught his two targets for 17 yards before exiting.

Sanders has been the change-of-pace back behind Javonte Williams this season, and that role will likely be taken over by Hunter Luepke if Sanders misses time. Rookie RB Jaydon Blue is also on the roster, but has been a healthy inactive in each of their four games.

In his first three games of the season, Sanders rushed 18 times for 109 yards and a touchdown.

Stay tuned to DK Network for live updates on his injury.

Ciaran has been an editor for the DraftKings Network team since 2023. He graduated from the University of Arizona before attending Arizona State University for his master’s degree in sports journalism. Ciaran previously covered Phoenix Rising FC for Cronkite News before joining DraftKings. He is passionate about sports betting, and his biggest focus has always been on the NFL and soccer. You can find him on X at @Ciaran_Doyle7.
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