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DraftKings MNF Pick6 Fantasy Football Picks: Top Plays for Monday Night Football Week 4

DraftKings MNF Pick6 Fantasy Football Picks: Top Plays for Monday Night Football Week 4

Updated:

By: Blake Krass

Week 4 of the 2025 NFL season continues with a great Monday Night Football doubleheader, starting with the Jets and the Dolphins, followed by the Bengals and the Broncos. There are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this season is Pick6 Fantasy Football!

Here are my top Pick6 plays for Monday Night Football.


De’Von Achane More than 0.5 Rush + Receiving Touchdowns

De’Von Achane had a breakout 2024-25 season, going for 1,499 yards from scrimmage. He led all running backs in receiving yards and ranked seventh in the NFL in yards from scrimmage. He is averaging 96 scrimmage yards per game so far this season, doing it on the ground and through the air. The Dolphins are 0-3 and have struggled massively in this game. This is a must-win game for Miami against the also 0-3 Jets. This should be a maximum effort game from Miami, and it will lean on its star running back. This should be a high-scoring game, with both defenses struggling this season. The Jets rank 28th in defensive EPA/play, and the Dolphins rank dead last. The back-and-forth nature of the game should present a lot of scoring opportunities for Achane. He has a great chance to get his third touchdown of the season against the Jets, a team he scored against in both matchups last season.

Chase Brown More Than 18.5 Receiving Yards

It has been a struggle for Chase Brown this season. He is averaging just 31 rushing yards per game after a great 2024-25 season. The loss of Joe Burrow has really hurt the Bengals’ offense. In their first game with Jake Browning at quarterback, the Bengals’ offense was unable to get anything going. Brown shockingly only rushed for three yards in that game against the Vikings. The Bengals were unlucky to face the best defensive coach in football, Brian Flores, in the first game with Browning at the helm. There should be a bounce-back for Cincinnati in this game. Browning has NFL experience and played well in 2023 when he started a run of games. The one thing Browning did do last week was feed Chase Brown in the pass game. Brown had four catches on five targets, and he should be used in the passing game again this week as well. The Bengals have issues on the offensive line and will likely struggle to run the ball all season. That will make Brown more of a weapon in the passing game, which should get him over this number.

J.K. Dobbins More Than 66.5 Rushing Yards

J.K. Dobbins is off to a great start to his Broncos career. Dobbins is very talented, but he has struggled to stay on the field throughout his career. He has suffered through several major injuries, but if he can stay healthy, he should be a great weapon for the Broncos. He is averaging 74 rushing yards per game so far this season and has a touchdown in all three games. Bo Nix has struggled so far this season, so Denver should rely on its run game to keep the ball away from Ja’Marr Chase and the Bengals’ great skill position players. The Bengals rank 26th in the NFL in defensive EPA/rush, but they rank 15th in defensive EPA/dropback. That is even more reason for the Broncos to lean on the run game and exploit the Bengals’ vulnerabilities on the defensive line. Dobbins has been running well and getting a lot of touches, so this should be a great chance for him to get over this number for the third straight game.


What is DraftKings Pick6?

Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.

How to Play

Create a Pick Set

Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice, and you must pick players from at least two different teams.

Enter an Amount

Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.

Sweat Your Picks

When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.

Compete for Prizes

Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.


Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!

Blake Krass has contributed to DraftKings since 2024, and is a content creator with a specialty in sports betting. Blake primarily focuses on college football and NFL coverage but will also be covering college basketball, the NBA, MLB and more. Prior to arriving at DK, Blake was a sports betting writer for The Action Network.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and customer (my username is blakekrass) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.