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Best College Football Player Prop Bets for LSU Tigers vs. Ole Miss Rebels Saturday 9/27/25

Best College Football Player Prop Bets for LSU Tigers vs. Ole Miss Rebels Saturday 9/27/25

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By: Bryan Armetta

In the eternal battle that is the SEC, every week matters. On a jam-packed Saturday slate, #4 LSU vs. #13 Ole Miss is must-watch television. Brian Kelly vs. Lane Kiffin…what more could a college football fan ask for? There’s plenty of star power on the sidelines for both of these programs. Which names will step up this afternoon?

These are the top college football player props to consider at DraftKings Sportsbook for the Week 5 matchup between the Louisiana State Tigers and the Ole Miss Rebels.

Ole Miss enters this contest as 1.5-point favorites over LSU, with the over/under set at 56.5 points on DraftKings Sportsbook.

LSU vs. Ole Miss best prop bets

Trinidad Chambliss 53+ rushing yards (-115)

All the talk in Oxford has revolved around Ole Miss’s newest quarterback. Ever since Austin SImmons’ injury in Week 2 (ankle), backup Trinidad Chambliss has been nothing short of phenomenal. The senior has thrown for 719 yards and four touchdowns. In addition, he leads the SEC with 11.6 yards per attempt. However, passing success could be difficult on Saturday. LSU has already flustered a pair of terrific passers in Cade Klubnik and DJ Lagway. It’s difficult to imagine anyone, even Chambliss, dominating this Tigers secondary.

With that being said, passing isn’t the only way to make an impact. Ole Miss’s QB is also a gifted scrambler. Through three games, Chambliss has gained 195 yards and two touchdowns as a rusher. It’s worth noting that most of this production came against Arkansas and Tulane. Saturday’s showdown is a whole different level of competition. However, as previously mentioned, the Tigers thrive at taking away big passing gains. If anything, Kiffin might opt for a safer, more run-oriented approach that keeps LSU’s offense on the bench. Don’t be shocked if Chambliss makes his biggest impact outside of the pocket tonight.

Bauer Sharp 28+ receiving yards (-116)

When discussing LSU’s pass catchers, names such as Aaron Anderson and Barion Brown garner the most excitement. However, All-American quarterback Garrett Nussmeier makes an effort to spread the ball around. That should be the case on Saturday, especially if Kiffin opts to double-team Anderson. Much like the Rebels, LSU would rather hold the ball for as long as possible. That means if the Tigers do throw the ball, it’s more likely to be a short or intermediate pass. The most obvious beneficiary of that game plan would be Bauer Sharp.

The former Oklahoma tight end is emerging as a weapon in Baton Rouge. Over his last two games, the senior has hauled in eight catches for 144 yards and a touchdown. It’s also worth noting that LSU has held a significant lead in all four of its contests this season. Going up against a dynamic Rebels offense, the Tigers might be forced to throw the ball. Last season, as a member of the Sooners, Sharp recorded a career-high 53 receiving yards vs. Ole Miss. With an elite quarterback throwing to him this time, the TE should put up similar, if not better, numbers.

Bryan Armetta is a New York-based writer that has spent over eight years in sports media. Working for DraftKings since 2024, he currently serves as a writer, editor and analyst for all things sports and pop culture. Bryan specializes in MLB, NBA, NFL, college sports and entertainment content. Prior to his time at DKN, he worked for MLB Network, NHL Network and SiriusXM Sports.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.