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Kyler Murray best prop bets for Cardinals vs. Seahawks on Thursday 9/25/25

Kyler Murray best prop bets for Cardinals vs. Seahawks on Thursday 9/25/25

Published:

By: Alex Hunter

The Cardinals are hosting the Seahawks on Thursday Night Football. On DraftKings Sportsbook, Seattle is favored by 1.5 points and this game carries a total of 43.5 points.

Below, I have featured my favorite Kyler Murray prop to consider from this contest.

Best Kyler Murray Prop Bets on DraftKings Sportsbook

Kyler Murray O 29.5 Rushing Yards (-110)

Kyler Murray is struggling mightily as a passer this season, averaging a terrible 5.4 YPA, which ranks third-to-last among quarterbacks this season. However, the dual-threat quarterback has been effective as a rusher, rushing for 38, 32 and 37 yards in his first three starts. Murray ranks fourth among quarterbacks with 6.7 carries per game and he is averaging 5.4 YPC.

Murray is facing the Seahawks on Thursday and this divisional matchup is a spot that could result in the quarterback being very active with his legs. Seattle has the seventh-highest graded defense on PFF this season and the club is pressuring quarterbacks at the fourth-highest rate in the league (44.3%).

The heavy pressure from the Seahawks’ defensive line could force Murray to scramble more than usual and he should top 29.5 rushing yards in this matchup, possibly with ease.

Alex Hunter is an avid DFS player and sports handicapper, who has been a proud member of the DraftKings Network team since 2020. He is a data-driven analyst, who earned his bachelor’s degree in communications at Worcester State University and has been in the sports content business for nearly a decade, covering the NBA, NFL and PGA TOUR. Alex is a diehard Boston Celtics fan, who loves to be on the golf course when he isn’t grinding lineups or producing content. For all of Alex’s work or if you need any lineup advice, be sure to follow him @Hunta512 on X.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is Hunta512) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.