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What happened to James Conner? Live injury updates for NFL Week 3 on 9/21/25

What happened to James Conner? Live injury updates for NFL Week 3 on 9/21/25

NFL

Updated:

By: Griffin Wong

UPDATE: Conner will require season-ending surgery on his right ankle.

UPDATE: Conner could miss the rest of the season with an ankle injury but is still waiting on an official prognosis, per ESPN.

Early in the third quarter of the Arizona Cardinals’ game against the San Francisco 49ers on Sunday afternoon, running back James Conner went down awkwardly after a one-yard rush. He suffered an ankle injury on the play, and the Cardinals team spilled onto the field to support him as he was carted back to the locker room. Very swiftly, he was ruled out for the remainder of the contest.

Stay tuned to DK Network for live updates on his injury.

Griffin Wong
Griffin Wong has been a content writer at DK Network since November 2024. Prior to that, he was the former sports editor for the Harvard Crimson, where he covered the football team for two years and earned four Story of the Year nominations from the Associated College Press. A lifelong Lakers and Dodgers fan, Griffin’s favorite athlete of all time is Kobe Bryant. When he’s not writing, Griffin is usually skiing, running, golfing, or playing basketball — badly.
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