The NASCAR Cup Series playoffs begin with the Round of 16 at the Cook Out Southern 500. The race takes place at Darlington Raceway in Darlington, South Carolina.
Denny Hamlin, who won Saturday’s qualifying race, is the favorite to to win the race on DraftKings Sportsbook. He is +450 to win.
Behind Hamlin are William Byron (+500), Kyle Larson (+600) and Ryan Blaney (+650).
The 2025 Cook Out Southern 500 will take place on Sunday, Aug. 31 at 6 p.m. ET.
Here are the full odds for each driver on DraftKings Sportsbook.
| Driver | Odds |
| Denny Hamlin | +450 |
| William Byron | +500 |
| Kyle Larson | +600 |
| Ryan Blaney | +650 |
| Christopher Bell | +700 |
| Chase Briscoe | +800 |
| Tyler Reddick | +850 |
| Chase Elliott | +1400 |
| Josh Berry | +1600 |
| Bubba Wallace | +1600 |
| Ross Chastain | +1600 |
| Joey Logano | +1800 |
| Chris Buescher | +2500 |
| Brad Keselowski | +2800 |
| Austin Cindric | +3000 |
| Kyle Busch | +3500 |
| Ty Gibbs | +4000 |
| Erik Jones | +5000 |
| Alex Bowman | +5000 |
| Ryan Preece | +5000 |
| Carson Hocevar | +5500 |
| Justin Haley | +6500 |
| Austin Dillon | +9000 |
| Daniel Suarez | +13000 |
| Michael McDowell | +15000 |
| Noah Gragson | +17000 |
| John Hunter Nemechek | +20000 |
| AJ Allmendinger | +20000 |
| Zane Smith | +20000 |
| Todd Gilliland | +20000 |
| Shane van Gisbergen | +20000 |
| Cole Custer | +25000 |
| Ricky Stenhouse Jr. | +25000 |
| Cody Ware | +40000 |
| Ty Dillon | +50000 |
| Derek Kraus | +80000 |
| Riley Herbst | +80000 |