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Cincinnati Reds vs. St. Louis Cardinals prediction, pick for Sunday 8/31/25

Cincinnati Reds vs. St. Louis Cardinals prediction, pick for Sunday 8/31/25

Published:

By: Charlie Cummings

With the MLB stretch run heating up, the NL Wild Card race looks like it will come down to the wire. The field is tight, with only a few teams still in realistic striking distance โ€” and the Cincinnati Reds and St. Louis Cardinals are two with an outside shot at making a playoff push.

The Reds enter as -137 moneyline favorites on DraftKings Sportsbook, with the over/under set at 8.5 runs.

Letโ€™s break down a quick preview, prediction, and best bet for this Reds vs. Cardinals matchup.


Reds vs. Cardinals prediction, preview

Following Saturdayโ€™s action, both the Reds and Cardinals remain within six games of the final Wild Card spot. Needless to say, this series is critical for both teams. Before Saturday’s game, the Reds had postseason odds of approximately 7%, per Baseball Reference, while the Cardinals sat just above 1%.

Unfortunately for St. Louis, starterย Andre Pallanteย is in the midst of a brutal stretch. Heโ€™s taken the loss in five straight starts โ€” and the last four have been fully earned. Over his previous four outings, Pallante owns anย 11.65 ERA, struggling to miss bats, issuing free passes, and giving up the long ball. With the Cardinals’ season hanging by a thread, the timing couldn’t be worse.

On the other side, Reds starterย Brady Singerย is trending in the opposite direction. In his last six starts, Singer has allowedย one or fewer earned runs in fiveย of them, pitchingย six or more inningsย each time. Cincinnati won all five of those outings. While this may seem like an even pitching matchup on paper, recent form makes it anything but.

Both teams feature solid bullpens and average offenses, but theย clear edge lies on the moundย โ€” and thatโ€™s enough to tilt the balance toward Cincinnati.

Best Bet: Cincinnati Reds -1.5 (+152)

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.