This is the second of a four-game series in Chicago between the White Sox and visiting New York Yankees.
Carlos Rodon is scheduled to pitch for New York, while Yoendrys Gomez is slated to start for Chicago.
White Sox vs. Yankees prediction, preview
Carlos Rodón is enjoying his best season yet as a New York Yankee in 2025, posting a 14-7 record with a 3.24 ERA, 1.07 WHIP, and 172 strikeouts over 158 innings pitched. He’s been particularly sharp lately, winning each of his last three starts while allowing no more than two earned runs in any of them. That said, his performance has been stronger at home, where he owns a 2.86 ERA at Yankee Stadium compared to a 3.62 mark on the road.
Yoendrys Gómez is set to make just his fourth start of the season after beginning the year in the bullpen. Since transitioning to the rotation, the former Yankee has impressed, picking up two wins and allowing no more than three earned runs in any of his three starts. He’s coming off a strong outing as well, tossing 4 2/3 scoreless innings against the Twins his last time out.
The Yankees are on a roll right now, fresh off a three-game sweep of the Nationals at home, where they piled up 26 runs across the series. They kept the momentum going by taking the opener of this series last night. It’s not just the team that’s heating up—Giancarlo Stanton has been on an absolute tear since returning from the injured list. “Big G” is batting .313 with 17 home runs and 46 RBIs in just 51 games so far in 2025, providing a major spark to the heart of the lineup.
White Sox vs. Yankees pick, best bet
The Yankees have consistently taken care of business against subpar opponents—and the White Sox fit that mold perfectly. With the entire lineup swinging hot bats right now, I’m more than comfortable backing New York on the run line at -137. Add in Carlos Rodón facing his former team, and I expect him to dominate and keep Chicago in check.