DKNetwork Logo DKNetwork Logo
Chicago Cubs vs. Cincinnati Reds prediction, pick for Monday 8/4/25

Chicago Cubs vs. Cincinnati Reds prediction, pick for Monday 8/4/25

Updated:

By: Dan Johnson

Below, I’ve got my preview, prediction, and best bet for this Monday night baseball game between the Cubs and the Reds.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Cubs vs. Reds prediction, preview

Nick Lodolo has been sharp—there’s no doubt about that. But he’s also allowed 15 homers to righties this year, and now he faces a Cubs lineup that skews right-handed with Seiya Suzuki, Christopher Morel, and Nico Hoerner all swinging well. Lodolo’s 3.09 ERA is impressive, but his FIP sits closer to 3.80, and the Cubs have been quietly dangerous at home. They’ve gone Over in three of their last five, and they’re slugging .438 at Wrigley since the break.

On the other side, Soroka’s underlying issues haven’t gone away. Left-handed hitters have tagged him for eight homers in 172 ABs and a .244 average. Cincinnati counters with Elly De La Cruz and Will Benson—both capable of putting one in the seats if the wind carries. And with warm weather and a breeze blowing out to left-center, expect a ball or two to get up and out.

Reds vs. Cubs pick, best bet

Factor in the recent bullpen usage—Cincinnati leaned on its relievers for seven innings just two days ago—and both managers may be slower to the hook. That only adds fuel to the total. Lodolo may give the Reds six decent innings, but Soroka’s volatility plus a stretched relief corps for both sides open the door late.

We’re getting this total at 7.5, with light juice to the Over. That’s a green light. Two capable but imperfect arms, homer-friendly weather, and multiple lineup threats suggest there’s enough firepower on both sides. I’ve got this finishing in the 5–4 or 6–3 range.

Cubs offense has been lifeless recently. Bounce back tonight against Lodolo.

Best bet: Cubs vs. Reds o7.5 total runs (+105)

Tail it with me in the DKN Betting Group here!

Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.