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MLB DFS Picks: Top DraftKings Targets and Values for Monday 7/21/25

MLB DFS Picks: Top DraftKings Targets and Values for Monday 7/21/25

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By: Garion Thorne

We’re nearing the 100-game mark of the regular season for many teams, which means the baseball will only continue to get spicier and more important. Tonight is a perfect example, as the Yankees travel north of the border to square-off with the Blue Jays in a battle for AL East supremacy.

How much will that tilt impact Monday’s 10-game featured MLB DFS slate on DraftKings? Let’s dive in and find out.

Set your DraftKings fantasy baseball lineups here: MLB $200K Knuckleball [$50K to 1st]


PITCHER

Stud

Kodai Senga, New York Mets vs. Los Angeles Angels, $9,300 – To be clear, Senga’s 1.39 ERA is an anomaly. I know that. Still, a 3.17 xERA and a 3.17 FIP across 77.2 innings isn’t too shabby. Nor is a 12.6% swinging strike rate. Senga might not be thiiiiiis good, but he’s still quite good. Now he’ll get to face an Angels team that owns the league’s second-highest strikeout rate (25.8%). The one thing Los Angeles does well in 2025 is hit home runs. Unfortunately for them, Senga’s been one of the best at negating opposing power numbers. Equipped with a career-high 47.5% ground ball rate, Senga has conceded just 0.46 long balls per nine in his 14 starts.

Value

Jacob Lopez, Athletics at Texas Rangers, $6,800 – First and foremost, it’s a plus that this contest is not taking place at Sutter Health Park. Secondly, it’s time to start talking about Lopez as a legitimate DFS asset. Over his last seven starts, Lopez is in possession of a 2.52 ERA, a 3.12 FIP and a 28.9% strikeout rate. The lefty’s velocity isn’t overpowering, but Lopez’s funky delivery and 93rd percentile extension have combined to frustrate opposing hitters. In fact, both Lopez’s fastball and slider have registered a whiff rate over 30% so far in 2025. He’ll look to keep his recent success going tonight against a Rangers lineup that has struggled with LHPs all year long. Texas is batting only .216 with a 71 wRC+ within the split.

INFIELD

Stud

Ivan Herrera, St. Louis Cardinals at Colorado Rockies, $5,500 – Herrera hasn’t missed a beat since returning from the IL last week, with four hits in his first four games back. Now he’ll get the pleasure of facing-off with Austin Gomber ($4,500) in Colorado. To be fair, Gomber has only made six starts in 2025, but he owns a 7.36 ERA at Coors Field and he’s surrendering 1.88 opponent home runs per nine. This is obviously a spot to attack. For his part, Herrera has crushed left-handed pitching in 2025, mustering a .391 ISO and a 228 wRC+ in his 58 plate appearances within the split. It’s all small samples, yet I’m willing to take my chances.

Stud

Eugenio Suarez, Arizona Diamondbacks vs. Houston Astros, $5,200 – Suarez might not be on the Diamondbacks much longer, but he’s certainly leaving an impression. The 34-year-old has hit a pair of home runs in back-to-back games, bringing his total for the season to 35. Among all qualified hitters, Suarez’s .344 ISO is the third-best mark in all of baseball, trailing only Aaron Judge and Cal Raleigh. Pretty good company! On Monday, Suarez and the rest of Arizona’s lineup with draw the left-handed Colton Gordon ($6,900), who has allowed opposing RHBs to bat .306 with a 1.94 home runs per nine. Advantage: Suarez.

Value

Willy Adames, San Francisco Giants at Atlanta Braves, $4,200 – The Giants just got swept by the Blue Jays, but it wasn’t Adames’ fault, as the shortstop smashed a pair of no-doubt home runs on Saturday. San Francisco’s big free agent addition is finally heating up in July, slashing .291/.361/.655 with a 181 wRC+ in 15 games. Adames also has some history with Bryce Elder ($6,300) — tonight’s starter for the Braves — with a pair of long balls and a double in 13 career at-bats. That level of individual success tracks, too. Elder has some ugly reverse-splits in 2025, giving up 1.99 home runs per nine to opposing RHBs. Woof.

OUTFIELD

Stud

Seiya Suzuki, Chicago Cubs vs. Kansas City Royals, $5,100 – The wind is supposed to be blowing in tonight at Wrigley, which isn’t ideal, but it’s still difficult to ignore Suzuki against a southpaw. In 122 plate appearances within the split, Suzuki owns a .392 wOBA and a 157 wRC+. In fact, among players with at least 75 PAs versus LHPs this season, Suzuki’s .427 expected wOBA is the eighth-highest mark in MLB. Noah Cameron ($8,000) is due for some regression. Why not start this evening in Chicago?

Value

Jurickson Profar, Atlanta Braves vs. San Francisco Giants, $3,600 – Profar hasn’t been amazing since returning from his 80-game suspension, but he does sport a .217 ISO and a 102 wRC+ across 62 plate appearances. At this price, that’s more than enough to be viable when batting out of Atlanta’s leadoff spot. It also helps that Hayden Birdsong ($6,600) is getting the start for the Giants. Birdsong has some decent stuff, yet he’s struggled in the rotation in 2025, with a 5.10 ERA in his nine starts. Birdsong has had his issues with LHBs, as well. Lefties have combined to hit 2.08 home runs per nine off the right-hander with a .390 wOBA.

Garion is a Toronto-based writer who has been playing fantasy sports since elementary school. With a particular affinity for advanced statistics and sabermetrics, he’s been covering DFS Baseball, Football and Basketball for DraftKings dating back to 2018. Prior to that, Garion’s work could be found at FNTSY, SportsGrid, HoopsHype, The New York Daily News and Sportsnet.ca. Still, he is a Dolphins fan, so his decision-making can be questioned from time-to-time.
Disclaimer

All views expressed are my own. I am an employee of DraftKings and am ineligible to play in public DFS or DKSB contests.