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Minnesota Twins vs. Chicago Cubs prediction, pick for Wednesday 7/9/25

Minnesota Twins vs. Chicago Cubs prediction, pick for Wednesday 7/9/25

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By: Dan Johnson

Who knew this would become a consequential series for both teams’ respective standings positions? Minnesota seized Game 1 via an 8-1 rout. Byron Buxton and Ryan Jeffers each delivered multi-big-hit nights, fueling home-field momentum in their Wild Card chase. Chicago stands atop the NL Central at 54-37, rebounding swiftly off last night’s blowout defeat. Both clubs need this win to govern division races and build series advantage heading toward Thursday’s finale. Below, I’ve got my preview, prediction, and best bet for this Wednesday night baseball game between the Twins and the Cubs.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Twins vs. Cubs prediction, preview

Chicago has surged to a 54-37 mark, leaning on a fourth-ranked wOBA (.343) and third-ranked ISO (.200) against righties this season. The Twins slump at 44-47, boasting just a .309 OBP and a 5.10 home bullpen ERA that bleeds runs late. Tonight’s opener loss fuels Chicago’s revenge edge in this revenge-spot system, and I’m striking fast.

Cade Horton brings a 4.15 ERA and 1.38 WHIP into his tenth start, pairing a 16.9% strikeout rate with a concerning 1.04 HR/9. His ground-ball tilt (47.9%) can suppress extra-base hits, but a 7.1% walk rate exposes him to damage from Minnesota’s patient hitters. On the bump for the Twins, David Festa has surrendered 1.48 HR/9 and owns a 5.48 ERA with a 1.36 WHIP. His 24.2% K-rate flashes upside, but a 39.2% ground-ball rate and 4.51 FIP underline a propensity for hard contact and extended innings.

Critics will point to the Cubs’ 1-2 road trip in their last three games, including an 8-1 shellacking on this same field. They’ll argue Minnesota’s 5-1 home stretch suggests a momentum swing. I refute that narrative with advanced splits: the Cubs rank second in xwOBA (.338) over their last seven days, while the Twins sit 25th in BABIP (.280) over the same span. Chicago’s lineup thrives on mistake pitches, and Festa’s career .317 opponents’ average demands those mistakes.

In Chicago’s order, Kyle Tucker posts a 141 wRC+ and .220 ISO over the last 14 days, torching fastballs. Seiya Suzuki’s .380 wOBA and 25.3% hard-hit rate over the past week anchors the heart of this order. Michael Busch racks a 132 wRC+ and .360 wOBA this month, driving extra-base hits as Chicago’s cleanup hitter. Pete Crow-Armstrong fuels the top order with a .336 xwOBA and 24.5% walk rate over his last 15 games.

On Minnesota’s side, Byron Buxton slugged .610 with a 155 July wRC+ and 47.5% hard-hit rate this month. Trevor Larnach holds a .345 xwOBA and an 18.4% strikeout rate across his last ten games. Ryan Jeffers had a big night on Tuesday, but so, too, did most of the Twins’ lineup against Shota Imanaga.

Cubs vs. Twins pick, best bet

From a purely betting lens, Chicago has a 17-8 ATS road record when favored between -100 and -150, returning plus-units in those spots all season. Head-to-head history favors the Cubs’ bounce-back: they’ve covered in five of their last six against these Twins. Weather conditions call for calm winds blowing in from left at about eight miles per hour, tilting the scale toward a punch-and-counter style game. Both bullpens rank middling, but Chicago’s relief group posts a 3.40 ERA compared to Minnesota’s 5.10 mark at home.

I’m locking in the Chicago moneyline at -110 and backing the visitors to rebound decisively. Cade Horton will navigate deep enough to hand off to a sharper pen, and Chicago’s lineup will exploit Festa’s inconsistent arsenal. It’s the Cubs’ bullpen that’ll cash this bet.

Revenge game spirit is really greasing the runway, here. Go Cubs.

Best bet: Cubs (-110) at Twins

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Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.