The 2025 MLB season is heating up and there are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this year is Pick6 Fantasy Baseball!
Here are my top Pick6 plays for today’s MLB slate.
Jarren Duran More Than 0.5 Home Runs
Nobody in baseball has taken more at-bats this season than Jarren Duran. It has been a bit up and down in terms of his production, but he is always dangerous at the plate. Duran only has five home runs on the season, but he is the major league leader with eight triples. His 20 doubles are tied for ninth in the MLB as well. Duran has struggled to get the ball over the fence, but he ranks 25th in the MLB in extra-base hits. That demonstrates that he is still putting the barrel on the ball, and soon, it will start going over the fence. Duran has crushed Jose Berrios in the past, so tonight would be the perfect time to hit a home run. Duran is 10-for-21 with five doubles and three home runs in his career against Berrios. That comes out to a 1.143 slugging percentage. Duran has a great chance to go deep in this one.
Juan Soto More Than 0.5 Hits
Juan Soto is one of the hottest hitters in baseball at the moment. Over the last 30 days, he is batting .319 with a 1.200 OPS. That is the highest OPS of any player with at least 50 at-bats over that stretch. He has eight hits in his past six games and should keep that going against Mitch Keller. Often, the only thing that prevents Soto from getting a hit is how much he gets walked. To Keller’s credit, he doesn’t walk a lot of batters. In fact, he hasn’t walked more than two batters in any of his past eight starts. His 2.30 walks per nine innings ranks 21st in baseball among eligible pitchers, so he will try to go after Soto, for better or for worse. Soto should keep his hot bat going and pick up a base hit against Keller.
Tommy Pham Less Than 0.5 Singles
Tommy Pham is having a tough season in Pittsburgh. He is slashing .223/.298/.277 with a 62 OPS+. Pham will be facing off against David Peterson tonight, who has been great this season. Peterson has a 2.98 ERA and is one of seven pitchers in baseball with a complete game shutout this season. Pham has been horrific against left-handed pitching this season. His .159 batting average against left-handed pitching is the 17th-worst mark in baseball for qualified hitters. Pham is also 0-for-2 in his career against Peterson. Pham only has seven hits against left-handed pitchers all year and Peterson should be able to shut him down in this matchup.
Brendan Donovan More Than 1.5 Total Bases
Brendan Donovan has been great for the Cardinals this season. Donovan is batting .301 with a 122 OPS+ so far this season. He is one of just 15 qualified hitters who are still batting over .300 at this point in the season. He has been even better against right-handed pitching, with a .344 batting average against righties. That is second only to Aaron Judge in batting average against right-handers. Donovan has raked off Luis Ortiz in the past as well. In his career, Donovan is 5-for-6 with two doubles against Ortiz. Ortiz is a sporadic pitcher who will give up hits in bunches when things start to go wrong. Donovan should be able to keep up his great season against righties and his great record against Ortiz and pick up an extra-base hit in this game.
Ronald Acuna Jr. More Than 2.5 Hits + Runs + RBIs
Ronald Acuna Jr. has been on fire since returning from his injury. After missing most of the 2024 season and the start of 2025, Acuna is back like he never left. He has now played 31 games and is slashing .369/.485/.658 with a 1.143 OPS. He is not yet considered a “qualified hitter,” but he would be leading the MLB in batting average and rank second in OPS behind Aaron Judge if he had enough at-bats to qualify. He has somehow been even better over the past couple of weeks, specifically. In the last 15 days, he is batting .395 with a 1.226 OPS. Tonight, he is facing Mich Abel, who is making just his sixth career start. In his most recent start, he gave up four home runs against the Mets. Acuna should be able to generate power off Abel and get over this number.
What is DraftKings Pick6?
Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of two or more players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.
How to Play DraftKings Pick6
Create a Pick Set
Create a Pick Set by choosing two or more players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you cannot pick the same player twice and you must pick players from at least two different teams.
Enter an Amount
Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.
Sweat Your Picks
When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.
Compete for Prizes
Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.
Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!
