The 2025 MLB season is heating up. There are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this year is Pick6 Fantasy Baseball!
Here are my top Pick6 plays for today’s MLB slate.
Shohei Ohtani More Than 0.5 Home Runs (Promo Pick)
Shohei Ohtani had a historic 2024 season and is the heavy favorite to win another MVP award in 2025. Shohei Ohtani ranks second in baseball in total bases and third in home runs and OPS. Today, DraftKings Pick6 is boosting Ohtani to hit a home run from 1.2x to 2x. Ohtani has homered in two of his past three games, and always fares well in Colorado. He has a career 1.202 OPS at Coors Field and has specifically crushed Austin Gomber in the past. He is 4-for-11 with two home runs and a triple in his career against Gomber, and has a great shot to hit a home run in this game as well.

Isaac Paredes More Than 1.5 Hits + Runs + RBIs
Isaac Paredes is having a solid season in Houston. He currently leads the Astros in home runs and RBIs on the season. Today, he faces Christopher Sanchez and the Philadelphia Phillies. Paredes has been great against Sanchez when they have faced each other in the past, to the tune of 4-for-5 and a home run. All it will take is another hit that drives in a run for Paredes to get over this number. He can also be driven in by the great Jose Altuve, who is almost always behind him in the lineup, to get a run scored. Part of the reason that Paredes has such great RBI numbers is because Jeremy Pena bats in front of him, and Pena is batting .325 this season. With all of these factors in play, Paredes should be able to hit this combination prop against the Phillies.

Junior Caminero More Than 1.5 Total Bases
Junior Caminero is on a hot streak at the moment. Over the past two weeks, Caminero is slashing .326/.408/.651 with a 1.059 OPS. He has 24 RBIs in his past 24 games played, and just continues to rake for Tampa Bay. He has been particularly great against right-handed pitching, sporting a 115 tOPS+ against righties this season. He has at least one hit in eight of his past ten games, and often makes that an extra-base hit. That is all Caminero needs to record more than 1.5 total bases and get over this number. These teams faced off earlier this season with Michael Lorenzen on the mound. In that game, Caminero hit a double and a home run off Lorenzen. He should feel great seeing Lorenzen on the bump today and rack up another extra-base hit.

Heliot Ramos More Than 0.5 Hits
Heliot Ramos is having a solid season at the plate for the Giants. Ramos made his first All-Star Game in 2024, and his 2025 numbers have been even better for the most part. He has a 140 OPS+ this season, compared to last year’s mark of 125. Part of the reason for that is Ramos has found more power in this bat this season. He almost has as many doubles as he had all of last season, and is on pace to exceed his home run and RBI numbers by a decent margin. Ramos is riding a five-game hitting streak heading into Thursday’s game against the Marlins. Janson Junk is on the mound for the Marlins, and while he has been solid this season, he has only gone more than five innings once all year. That forces Miami to turn to its bullpen, which has a 4.43 ERA this season, the eighth-worst mark in baseball this season. Ramos should keep his hitting streak going in this game against the Marlins.

Juan Soto More Than 1.5 Hits + Runs + RBIs
Juan Soto is in the midst of one of the best months by any Met in the history of the franchise. While, as a team, the Mets are on a tough losing stretch, Soto has finally turned into the player that the Mets signed to a historic deal. In the month of June, he is batting .306, with a 1.238 OPS and ten home runs. He has combined for 40 runs and RBIs as well this month. That sets him up to go over 1.5 hits + runs + RBIs tonight against Grant Holmes. Holmes has a 3.71 ERA and a 1.24 WHIP this season, and Soto should be able to attack him. Holmes has also been much worse on the road, sporting a 4.58 ERA away from Atlanta. Soto’s hot bat should be able to clear this number in one swing.

Seiya Suzuki More Than 1.5 Total Bases
Seiya Suzuki has been an unsung hero for the Cubs this season. Pete Crow-Armstrong has taken the league by storm and is in the NL MVP conversation. However, Suzuki is the team leader in RBIs with 67. That is the second-most RBIs in all of baseball, behind only Cal Raleigh. He is tied for the sixth-most total bases in the MLB and has simply been a machine at the plate for Chicago. Suzuki should register more than 1.5 total bases today against the Cardinals as well. Suzuki is 3-for-4 with a double in his career against Andre Pallante. Pallante has a 4.48 ERA this season and has given up at least three runs in four of his past six starts. Suzuki should keep his great season going by racking up an extra-base hit in this game.

What is DraftKings Pick6?
Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of two or more players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.
How to Play DraftKings Pick6
Create a Pick Set
Create a Pick Set by choosing two or more players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you cannot pick the same player twice and you must pick players from at least two different teams.
Enter an Amount
Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.
Sweat Your Picks
When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.
Compete for Prizes
Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.
Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!