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Shohei Ohtani Best Prop Bet for Diamondbacks at Dodgers on Tuesday 5/20/25

Shohei Ohtani Best Prop Bet for Diamondbacks at Dodgers on Tuesday 5/20/25

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By: Ryan Wohl

Although the reigning and defending World Series champions are 29-19 this season, they have lost four straight games. The Dodgers are also 6-9 in their previous 15 games. After losing to the Arizona Diamondbacks 9-5 last night, they will host them in the second game of a four-game series tonight at 10:10 p.m. ET.

Even though the Dodgers have struggled as a team, their superstar Shohei Ohtani has been on fire. He has 10 hits, 10 RBIs, and five home runs in the last six games. Here is my favorite prop bet for Ohtani against the Diamondbacks tonight.

Shohei Ohtani 1+ Home Runs (+170)

This season, Ohtani is leading the MLB in home runs with 17, one more than Kyle Schwarber. After having only five home runs in the first full month of the season, Ohtani has hit 10 of them in the first 19 days of May. You can back Ohtani to hit another home run tonight against Ryne Nelson and the Diamondbacks at +170 on DraftKings Sportsbook.

The Dodgers are in the middle of their second series this season against Arizona. Ohtani hit three home runs in three of their five matchups this season, with his most recent one coming last night. Tonight, LA will be going up against Nelson, who is 1-1 with a 5.13 ERA this year. He has allowed three home runs this season and gave up one to Jung Hoo Lee from the San Francisco Giants in his last appearance on May 14.

Tonight, the Dodgers have Yoshinobu Yamamoto on the mound. He has gone 5-3 this season with a 2.12 ERA, and the Dodgers lost 5-3 the last time he pitched against the Diamondbacks this year. If the Dodgers want to snap their four-game losing streak, they will need an elite showing from Yamamoto and Ohtani. In Ohtani’s last 10 games against Arizona, he has hit five home runs, and another one seems likely tonight with a favorable pitching matchup.

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.