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Best Shohei Ohtani prop bet for Diamondbacks vs. Dodgers on Monday 5/19/25

Best Shohei Ohtani prop bet for Diamondbacks vs. Dodgers on Monday 5/19/25

Updated:

By: Ciaran Doyle

Shohei Ohtani and the Dodgers get set for the first of a three-game series against the Diamondbacks on Monday night. Brandon Pfaadt is the probable starter for Arizona, while Landon Knack is set to pitch for L.A. On DraftKings Sportsbook, the Dodgers are slight -148 favorites on the moneyline while the run total is set at 10.

Best Shohei Ohtani Prop Bet on DraftKings Sportsbook

Shohei Ohtani Over 2.5 Hits + Runs + RBIs (-115)

DraftKings Sportsbook lists Ohtani’s prop lines at 1.5 Hits, 1.5 total bases, 0.5 runs and 0.5 RBIs. He is +165 to hit a home run and his O/U Hits + Runs + RBIs is 2.5.

Ohtani has a very limited history against Brandon Pfaadt with only nine career at-bats against him. It’s a small sample size, but Ohtani has struggled against him with a .222 batting average, two hits and one RBI. However, Ohtani is too good to let that continue. There is a reason he leads the MLB in runs and home runs, and is a +110 favorite to win National League MVP this season on DraftKings Sportsbook.

He has gone over this hits + runs + RBIs total in four of his last five outings and is coming off a game with three hits, one run and one RBI on Sunday against the Angels.

Another thing Ohtani has on his side in this matchup is Pfaadt’s struggles away from Arizona. His ERA is 3.73 on the season, but it skyrockets to 6.64 on the road. In four games against Arizona so far this season, Ohtani has four runs, seven hits and six RBIs in only 19 at-bats. He has performed well against this ball club, and expect him to do the same on Monday night against a pitcher who struggles on the road.

Ciaran has been an editor for the DraftKings Network team since 2023. He graduated from the University of Arizona before attending Arizona State University for his master’s degree in sports journalism. Ciaran previously covered Phoenix Rising FC for Cronkite News before joining DraftKings. He is passionate about sports betting, and his biggest focus has always been on the NFL and soccer. You can find him on X at @Ciaran_Doyle7.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is ciarandoyle77) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.