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MLB DFS Picks: Three must-start fantasy baseball players for Friday 5/9/25

MLB DFS Picks: Three must-start fantasy baseball players for Friday 5/9/25

Updated:

By: Garion Thorne

It’s Friday — Friday. You got to get down on Friday.

You also need to read this article about my top three MLB DFS picks for Friday’s 12-game featured slate on DraftKings. Rebecca Black didn’t mention that part in the song, but it still counts.

Set your DraftKings fantasy basketball lineups here: MLB $200K Hidden Ball Trick [$50K to 1st]


SP Max Meyer, Miami Marlins at Chicago White Sox, $10,200

I have a feeling that Meyer is going to get overlooked on this slate.

Not only is this a shocking sticker price for a man with a career 5.12 ERA, but Meyer has struggled in his last two outings, surrendering five earned runs in each start. Add in the fact that Hunter Brown ($11,000) is only $800 more expensive, and it feels like the factors are stacked against Meyer this evening.

However, we’re still talking about a pitcher that is less than three weeks removed from a 14-strikeout, 42.5 FPTS performance against the Reds. Meyer didn’t strikeout a single opponent in his last appearance, yet his 28.1% strikeout rate remains elite. That contest was against the Athletics, who sport the league’s fourth-lowest strikeout rate (19.5%). On Friday, Meyer and the Marlins will square-off with the White Sox, who possess MLB’s fourth-highest strikeout rate (23.6%) and the American League’s lowest wRC+ (76). Needless to say, this is a completely different animal. At what should be a low ownership, I’ll take my chances with Meyer’s lofty upside.

OF Fernando Tatis Jr., San Diego Padres at Colorado Rockies, $6,500

He’s so, so expensive, yet I’ll be unable to avoid getting Tatis into a few lineups on Friday. Through 152 plate appearances in 2025, Tatis is slashing .319/.388/.548 with eight home runs, eight stolen bases and a 163 wRC+ that ranks ninth among qualified hitters. He’s also in possession of 96th percentile marks in both expected wOBA (.420) and expected slugging percentage (.601). In layman’s terms: He’s very good.

Still, this isn’t really about Tatis. It’s about Antonio Senzatela ($5,000) and Coors Field. Senzatela might just be the worst current starter that’s taking the mound every fifth day, as evidenced by a ghastly 7.01 xERA. RHBs have been particularly destructive against the Rockies’ RHP in 2025, clubbing an absurd 4.11 home runs per nine with a .477 wOBA. Somehow, in 15 career at-bats, Tatis only has one extra-base hit off Senzatela. That changes tonight.

2B Jackson Holliday, Baltimore Orioles at Los Angeles Angels, $3,600

I have no idea how the only pitcher that has stopped the red-hot Tigers in the past two weeks was Kyle Hendricks ($5,800), but whatever witchcraft the veteran RHP used last weekend has surely run dry. Hendricks is doing his usual thing so far in 2025, eating innings and pitching to a 5.28 ERA and a 5.55 FIP. The 35-year-old comes into Friday’s action with a third percentile strikeout rate (12.9%) and a fourth percentile whiff rate (16.7%). In other words, the Orioles are going to be drowning in batted ball events at Angel Stadium.

Meanwhile, let’s sing the praises of Holliday a little bit. It’s been lost in Baltimore’s hellish start to 2025, but the former No. 1 prospect in baseball has been solid in his sophomore campaign — especially against RHPs. In 88 plate appearances in the split this season, Holliday is slashing .272/.330/.457 with a 127 wRC+. He’s too cheap for his talent level and this matchup.

Garion is a Toronto-based writer who has been playing fantasy sports since elementary school. With a particular affinity for advanced statistics and sabermetrics, he’s been covering DFS Baseball, Football and Basketball for DraftKings dating back to 2018. Prior to that, Garion’s work could be found at FNTSY, SportsGrid, HoopsHype, The New York Daily News and Sportsnet.ca. Still, he is a Dolphins fan, so his decision-making can be questioned from time-to-time.
Disclaimer

All views expressed are my own. I am an employee of DraftKings and am ineligible to play in public DFS or DKSB contests.