Friday’s MLB Prop Bets article will cover the full slate of games starting at 6:10 p.m. ET. If you want to tail any of these bets, you can find them on DraftKings Sportsbook. To easily get to the betting page, click on the headline for the bet below to be taken to it on DraftKings Sportsbook.
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MLB Prop Bets for Friday, May 2, 2025
New York Yankees team total bases over 13.5 -115
The Yankees face Ryan Pepiot of the Rays tonight, leading me to favor the over on the Yankees’ team total bases. Pepiot has allowed many extra-base hits, surrendering 18, including eight home runs, in six starts. The Yankees, a power-hitting team, lead the league with a slugging percentage (SLG) of .478. Pepiot throws four-seam fastballs 39% of the time, and the Yankees’ expected lineup tonight has an isolated power (ISO) of .262, making them well-suited to capitalize on his pitching. Therefore, I’m confident in taking the over on the Yankees’ team total bases of 13.5.
Aaron Judge is one of my picks for the debut of DraftKings’ King of the Diamond promo. Read all about it on DraftKings Network.
DraftKings Sportsbook has launched King of the Diamond, which begins tonight, May 2. For all the information, picks, and strategy for this promotion, visit the King of the Diamond Picks article on DraftKings Network.
Luis Arraez over 0.5 runs scored +115
I initially considered betting on Luis Arraez to exceed 1.5 hits, runs, or RBIs, but I was surprised to see the odds priced at -180. Instead, I pivoted to betting on Arraez to score a run tonight against the Pirates. Mitch Keller, Pittsburgh’s starting pitcher, struggles against left-handed batters, posting a .350 weighted on-base average (wOBA) against them this season. Lefties have accounted for 12 of the 16 runs he’s allowed. Arraez, a left-handed batter, ranks fourth on the Padres with 10 runs scored. Given Keller’s struggles against left-handed hitters, I’m confident in betting on Arraez to score a run tonight.
San Francisco Giants over 4.5 runs -125
The Giants will be taking on the Rockies and starter Antonio Senzatela. It’s been a rough go for the Rockies starter, who has a bloated 5.22 ERA but an even worse 7.55 xERA and a 5.89 FIP. After somehow allowing zero runs through his first two starts, Senzatela has allowed 17 in his last 22.2 innings. The Giants have a great opportunity to pile onto those runs allowed in San Francisco. Senzatela has an overall .436 wOBA in 2025 and has an extremely high 2.1 HR/9.
DraftKings Sportsbook has launched King of the Diamond, which begins tonight, May 2. For all the information, picks, and strategy for this promotion, visit the King of the Diamond Picks article on DraftKings Network.
Good luck with these MLB picks for tonight!
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