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Baltimore Orioles vs. New York Yankees prediction, pick for Monday 4/28/25

Baltimore Orioles vs. New York Yankees prediction, pick for Monday 4/28/25

Published:

By: Dan Johnson

Alright, here we go—the Yankees are in Charm City, and they’re ready to handle business against a slumping Orioles squad. Will Warren’s improving form and Aaron Judge’s white-hot bat should be enough to push the Yankees to another win tonight. With the Yankees thriving both offensively and on the mound, they’re primed to claim this game and add to their division lead. Time for the Orioles to face reality! Below, I’ve got my preview, prediction, and best bet for this Monday night baseball game between the Orioles and the Yankees.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Orioles vs. Yankees prediction, preview

The Yankees are rolling into Oriole Park with their offense clicking and a clear edge in nearly every facet of the game. With a 17-11 record, they’ve outpaced the AL East, thanks in large part to the consistent power surge from Aaron Judge, who continues to dominate with a .406 average, eight homers, and 27 RBIs. As one of the most dynamic forces in baseball, Judge’s ability to drive in runs and keep the lineup moving makes New York a formidable challenge. But the Yankees’ success isn’t just about one player. The lineup has depth: Ben Rice, now batting .259 with six homers, is providing extra pop, and the consistent contributions from guys like Paul Goldschmidt and Anthony Volpe round out a dangerous offensive machine. Their 45 home runs and .462 slugging percentage rank them near the top in the majors, making it tough for any pitcher, especially one who’s not overpowering, to silence them.

On the mound for New York is Will Warren, a 1-0 rookie who’s been steadily finding his rhythm, posting a 4.79 ERA in 20.2 innings this season. Warren hasn’t been perfect, but his fastball-slider combo is improving, and he’s shown signs of mastering the strike zone—key for success against a volatile Orioles lineup. Despite a modest K/9 rate of 9.15, he’s steadily missing more bats, which is crucial when facing a team like Baltimore that’s been struggling to generate consistent offense. The Orioles rank just 19th in runs scored this season and are stumbling with a .223 batting average. They’ve lacked the offensive consistency expected from a team that boasts Cedric Mullins, who leads with six home runs and 20 RBIs, but still remains too reliant on home runs for run production. The Orioles need more out of guys like Ryan O’Hearn and Adley Rutschman, both of whom have shown flashes of talent but haven’t delivered at the necessary clip.

Baltimore’s pitching hasn’t been any more reliable. Tomoyuki Sugano, their 35-year-old rookie, has been solid with a 3.54 ERA in five starts, but his low strikeout rate and reliance on contact could prove problematic against a Yankees team with such lethal power and discipline at the plate. Sugano isn’t likely to dominate this lineup; even though he’s pitched deep into games, his inability to overpower hitters leaves him vulnerable to the Yankees’ powerful bats.

Yankees vs. Orioles pick, best bet

Despite a decent effort from Sugano, the Orioles’ overall pitching staff has a 5.37 ERA, which ranks 30th in MLB. This will be a tall task when facing the Yankees, who have lit up weaker pitching staffs this season. The Yankees have already shown they can win games on the road (7-6) and their pitching staff, while not elite, is more than competent with a 3.70 ERA.

Baltimore’s bullpen hasn’t been much better, ranking 24th in ERA. This is a serious liability when you’re facing an offense that’s capable of busting open games in an instant. Add in the fact that the Yankees are 6-2 in their last eight road games against AL East teams with a losing record, and the clear advantage shifts to New York.

The Yankees are simply the better team in nearly every area. Their potent offense should overpower Sugano, and with Warren continuing to make strides, the Yankees are in a strong position to take this one by the number. They’ve covered the spread in four of their last five, and tonight’s matchup looks ripe for them to do so again. Having said that, I’m a little nervous the Orioles’ bats might wake up in frustration and fury, and it’s not like the Yankees have been road warriors. We’ll just take the Moneyline, here.

Best bet: Yankees ML (-125) at Orioles

Orioles still can’t get it right at home tonight; tail it with me in the DKN Betting Group here!

Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.