Our MLB Starting Pitchers page is your one stop to check out who’ll be taking the hill on Wednesday, April 16th. Here, you’ll see the matchups, opening lines and times the games are scheduled to begin. All odds and lines are provided by DraftKings Sportsbook.
For daily fantasy and betting information on this slate, visit DraftKings Network for daily MLB content and news.
MLB Starting Pitchers for April 16th, 2025
Atlanta Braves: Spencer Strider -148
Toronto Blue Jays Chris Bassitt +124
1:07 p.m. ET
Detroit Tigers: Keider Montero +120
Milwaukee Brewers: Jose Quintana -142
1:10 p.m. ET
New York Mets: TBD -102
Minnesota Twins: David Festa -118
1:10 p.m. ET
Houston Astros: Ronel Blanco -115
St. Louis Cardinals: Steven Matz -105
1:15 p.m. ET
Chicago Cubs: Matthew Boyd +105
San Diego Padres: Nick Pivetta -125
4:10 p.m. ET
Cleveland Guardians: Gavin Williams +110
Baltimore Orioles: Dean Kremer
6:35 p.m. ET
Arizona Diamondbacks: Brandon Pfaadt -166
Miami Marlins: Max Meyer +140
6:40 p.m. ET
Seattle Mariners: Bryce Miller -122
Cincinnati Reds: Nick Martinez +102
6:40 p.m. ET
Washington Nationals: Mitchell Parker -110
Pittsburgh Pirates: Bailey Falter -110
7:40 p.m. ET
San Fancisco Giants: Robbie Ray +124
Philadelphia Phillies: Aaron Nola -148
6:45 p.m. ET
Kansas City Royals : Kric Bubic +145
New York Yankees: Clarke Schmidt -175
7:05 p.m. ET
Boston Red Sox: Sean Newcomb +124
Tampa Bay Rays: Zack Littell -148
7:05 p.m. ET
Athletics: Osvaldo Bido -155
Chicago White Sox: Jonathan Cannon +130
7:40 p.m. ET
Los Angeles Angels: Jose Soriano -118
Texas Rangers: Patrick Corbin -102
8:05 p.m. ET
Colorado Rockies: German Marquez +250
Los Angeles Dodgers: Bobby Miller -310
10:10 p.m. ET
For daily fantasy and betting information on this slate, visit DraftKings Network for daily MLB content and news.
Follow me @SBuchanan24 on Twitter for daily MLB info and bets, including daily betting information about the most bet props, games and teams.
