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Shohei Ohtani best prop bets for Dodgers vs. Cubs on Friday 4/11/25

Shohei Ohtani best prop bets for Dodgers vs. Cubs on Friday 4/11/25

Published:

By: Brendan O'Sullivan

After starting the season 8-0, the Dodgers have lost four of their last six. They lost two games to both the Phillies, a National League contender, and the Nationals, a rebuilding team.

Los Angeles has another tough series with the Cubs visiting town for a three-game set. These two teams played a two-game series in Japan to kick off the season on March 18-19. Now that all MLB teams are playing, Chicago will look for redemption.

Despite the recent struggles, the Dodgers are still favored in this matchup. They are -192 on the moneyline and the game total is set at eight runs on DraftKings Sportsbook.

Below I have featured my favorite Shohei Ohtani prop bets to consider from tonight’s contest.

Best Shohei Ohtani Prop Bets on DraftKings Sportsbook

Shohei Ohtani 1+ home run (+300)

Ohtani may not have the most home runs on his team, but he’s still crushing the ball. He’s up to four homers through 14 games, which is just two behind MLB’s leaders.

Not only is he hitting for power, but he’s also batting an excellent .315 across 54 at-bats. This was highlighted during the Tokyo series as Ohtani had three hits in eight at-bats.

The Dodgers superstar will get another series against the Cubs and will face Matthew Boyd tonight. The two have limited history against each other as Ohtani is just 2-9 (.222) against the left-hander. That said, Ohtani’s expected batting average against Boyd is .318.

Ohtani’s expected slugging and on-base percentages also rise drastically compared to his actual stats against Boyd. It implies that Ohtani hasn’t had the best luck on balls he’s put into play against Boyd. If the two faced off more often, it’s likely that Ohtani’s averages would rise closer to his expected averages.

While this doesn’t mean Ohtani is guaranteed to play well against Boyd tonight, there’s a good chance he does. Pairing these stats with Ohtani’s strong start to his 2025 campaign makes his home run prop enticing at +300 value.

Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is osullivanb255) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.