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Jose Ramirez best prop bet for Guardians vs. White Sox on Wednesday 4/9/25

Jose Ramirez best prop bet for Guardians vs. White Sox on Wednesday 4/9/25

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By: Bryan Armetta

Two struggling squads will meet tonight when the 4-6 Guardians host the 2-8 White Sox. Cleveland, the reigning AL Central champions, has seen most of its hitters struggle this season. That doesn’t include Jose Ramirez, who currently leads the team with a .310 batting average. Can the 32-year-old lead his club to a victory over Chicago?

The Guardians are favored in tonight’s contest (-185), with the over/under set at 7.5 runs. Ahead of Wednesday’s matchup, here’s my favorite Jose Ramirez player prop bet on DraftKings Sportsbook.


Jose Ramirez O 0.5 RBIs (+165)

Even while playing on an offensively limited roster, Jose Ramirez knows how to drive runners in. Since 2022, the third baseman’s 330 RBIs trail only Aaron Judge (368), Pete Alonso (352) and Matt Olson (345). That level of production has continued this season; through nine games, J-Ram has crushed four homers while driving in six runners.

Cleveland’s face of the franchise has a promising matchup on paper tonight vs. Chicago. The South Siders will send Sean Burke to the mound; 2025 has been a mixed bag for the rookie. After a dominant outing on Opening Day, the right hander coughed up six runs in 4.1 innings vs. Minnesota. Last September, he held the Guardians to one run over three innings of relief work.

This season, Burke has thrown his fastball 35% of the time and his curveball 19% of the time. Ramirez is hitting .333 and .286 against both pitch types, respectively.

As good as the six-time All-Star is at the plate, he can’t do it alone. Fortunately, Steven Kwan is one of baseball’s most dependable leadoff hitters. So far, the outfielder leads Cleveland with a batting average of .316 and an on-base percentage of .366. There’s a good chance the 27-year-old puts himself or another runner in scoring position for Ramirez.

RBIs are never the easiest prop bet, as they are heavily dependent on the performance of an entire lineup. Still, the Kwan-Ramirez tandem has gotten to more experienced starters than Sean Burke. A locked-in J-Ram is difficult to avoid at +165 odds.

Bryan Armetta is a New York-based writer that has spent over eight years in sports media. Working for DraftKings since 2024, he currently serves as a writer, editor and analyst for all things sports and pop culture. Bryan specializes in MLB, NBA, NFL, college sports and entertainment content. Prior to his time at DKN, he worked for MLB Network, NHL Network and SiriusXM Sports.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.